Evidence map›Paper›PMID 32110915›Full record

ArticleMolecules (Basel, Switzerland)2020

Solvent-Free Iron(III) Chloride-Catalyzed Direct Amidation of Esters.

Blessing D Mkhonazi, Malibongwe Shandu, Ronewa Tshinavhe, Sandile B Simelane, Paseka T Moshapo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Blessing D MkhonaziResearch Centre in Synthesis and Catalysis, Department of Chemical Science, University of Johannesburg, PO Box 524, Auckland Park 2006, South Africa.
Malibongwe ShanduResearch Centre in Synthesis and Catalysis, Department of Chemical Science, University of Johannesburg, PO Box 524, Auckland Park 2006, South Africa.
Ronewa TshinavheResearch Centre in Synthesis and Catalysis, Department of Chemical Science, University of Johannesburg, PO Box 524, Auckland Park 2006, South Africa.
Sandile B SimelaneDepartment of Chemistry, University of Eswatini, Private Bag 4, Kwaluseni M201, Eswatini.
Paseka T MoshapoResearch Centre in Synthesis and Catalysis, Department of Chemical Science, University of Johannesburg, PO Box 524, Auckland Park 2006, South Africa.

Funding

National Research Foundation South Africa 118082
6 · The paper itself

Abstract

Amide functional groups are prominent in a broad range of organic compounds with diverse beneficial applications. In this work, we report the synthesis of these functional groups via an iron(iii) chloride-catalyzed direct amidation of esters. The reactions are conducted under solvent-free conditions and found to be compatible with a range of amine and ester substrates generating the desired amides in short reaction times and good to excellent yields at a catalyst loading of 15 mol%

Indexed as

AmidesAntitubercular AgentsCatalysisChloridesEstersFerric CompoundsLactamsPyrimidinesSolventsAmidesAntitubercular AgentsChloridesEstersferric chlorideFerric CompoundsLactamsPyrimidinesSolventsamidationamidesestersiron(III) chloridesolvent-free

Identifiers

PMID32110915
PMCPMC7179140

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.