Evidence map›Paper›PMID 32110899›Full record

ArticleInternational journal of environmental research and public health2020

Parameters of Oxidative Stress in Reproductive and Postmenopausal Mexican Women.

Araceli Montoya-Estrada, Karla Guadalupe Velázquez-Yescas, Daniela Belen Veruete-Bedolla, José David Ruiz-Herrera, Alma Villarreal-Barranca, José Romo-Yañez, Guillermo Federico Ortiz-Luna, Arturo Arellano-Eguiluz, Mario Solis-Paredes, Arturo Flores-Pliego and 3 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Araceli Montoya-EstradaCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Karla Guadalupe Velázquez-YescasCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Daniela Belen Veruete-BedollaCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
José David Ruiz-HerreraCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Alma Villarreal-BarrancaCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
José Romo-YañezCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Guillermo Federico Ortiz-LunaPeri and Postmenopause Clinic. National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Arturo Arellano-EguiluzPeri and Postmenopause Clinic. National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Mario Solis-ParedesDepartment of Human Genetics and Genomics, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Arturo Flores-PliegoDepartment of Immunobiochemistry, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Aurora Espejel-NuñezDepartment of Immunobiochemistry, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Guadalupe Estrada-GutierrezDirection of Research, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.
Enrique Reyes-MuñozCoordination of Gynecological and Perinatal Endocrinology, National Institute of Perinatology, Ministry of Health, México City 11000, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the reproductive phase, women experience cyclic changes in the ovaries and uterus, and hormones regulate these changes. Menopause is the permanent loss of menstruation after 12 months of amenorrhea. Menopause is also linked to a decrease in estrogen production, causing an imbalance in oxidative stress. We aimed to compare the three stages of lipid peroxidation, protein oxidative damage, and total antioxidant capacity (TAC) between reproductive-aged women (RAW) and postmenopausal women (PMW) in Mexico. We carried out a cross-sectional study with 84 women from Mexico City, including 40 RAW and 44 PMW. To determine the oxidative stress of the participants, several markers of lipid damage were measured: dienes conjugates (DC), lipohydroperoxides (LHP), and malondialdehyde (MDA); exposure to protein carbonyl is indicative of oxidative modified proteins, and TAC is indicative of the antioxidant defense system. Biomarkers of oxidative stress were significantly lower in RAW vs. PMW. DC were 1.31 ± 0.65 vs. 1.7 ± 0.51 pmol DC/mg dry weight (

Indexed as

Lipid PeroxidationOxidative StressPostmenopauseReproductionAdultAntioxidantsCross-Sectional StudiesFemaleHumansMalondialdehydeMexicoMiddle AgedYoung AdultAntioxidantsMalondialdehydemalondialdehydepostmenopauseprotein damagereactive oxygen speciestotal antioxidant capacity

Identifiers

PMID32110899
PMCPMC7084784

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.