ArticleVisceral medicine2020
Symptoms of Primary Hyperparathyroidism in Men and Women: The Same but Different?
Article in Visceral medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Multimodality imaging localization of a giant functional parathyroid adenoma in a young fitness trainer with delayed recognition of hypercalcemia: A case report.Radiology case reports · 2026Article
- Sex differences in the clinical presentation and complications of primary hyperparathyroidism: insights from a single-center cohort study.Endocrine · 2026Article
- PTH-induced behavioral and metabolic alterations in mouse models of hyperparathyroidism.iScience · 2026Article
- Paget's Disease of Bone and Normocalcemic Variant of Primary Hyperparathyroidism in an Osteoporotic Male: Exceptional Coexistence.Reports (MDPI) · 2025Article
- Intrathyroidal Fifth Parathyroid Adenoma: A Rare Cause of Primary Hyperparathyroidism.JCEM case reports · 2025Article
- An Analysis of Primary Hyperparathyroidism in Association with Depression or Anxiety.Diseases (Basel, Switzerland) · 2025Review
- [Gender medicine: endocrine and neuroendocrine diseases : Implications for surgery and perioperative management].Chirurgie (Heidelberg, Germany) · 2024Review
- [Localization diagnostics and operative strategy for the first intervention in sporadic primary hyperparathyroidism].Chirurgie (Heidelberg, Germany) · 2023Review
- Primary hyperparathyroidism in Saudi Arabia revisited: a multi-centre observational study.BMC endocrine disorders · 2022Observational
- A Pilot Study of the AssociationIn vivo (Athens, Greece)Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION AND
objectiveTypical symptoms for primary hyperparathyroidism (pHPT) include osteoporosis, bone or joint pain, and nephrolithiasis, as well as fatigue, depression, gastritis, and cardiovascular disease. The female:male ratio was 3:1. The aim of this retrospective study was to evaluate the possible influence of gender-specific aspects of these symptoms.
methodsFrom February 2018 to November 2019, parathyroid surgery was performed in 125 patients with pHPT (age: 23-83 years); 95 (76%) were female, and 30 (24%) were male. Preoperatively, a standardized medical history including 7 typical symptoms of pHPT was used for routine clinical documentation according to the StuDoQ Thyroid and Parathyroid Registry.
resultsFor both groups (mean age: 60.4 years for females and 60.2 years for males), no sex differences were found in serum calcium or parathyroid hormone levels. For females, there was a tendency towards smaller hyperfunctioning parathyroid glands (16.8 vs. 20.5 mm) with less weight (1.14 vs. 1.52 g) and multiglandular disease. Nephrolithiasis was significantly more frequent in men than in women (36.7 vs. 16.8%, respectively;
conclusion91.2% of patients transferred for parathyroidectomy described typical symptoms of pHPT. However, an unexpected high gender difference was found following the analysis of symptoms documented in the StuDoQ Registry.
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