ArticleGlobal advances in health and medicine2020
Dynamic Brain Activity Following Auricular Point Acupressure in Chemotherapy-Induced Neuropathy: A Pilot Longitudinal Functional Magnetic Resonance Imaging Study.
Article in Global advances in health and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Auricular point acupressure for older adults with chronic low back pain: a randomized controlled trial.Pain medicine (Malden, Mass.) · 2025Trial
- Retention, adherence, and acceptability testing of a digital health intervention in a 3-group randomized controlled trial for chronic musculoskeletal pain.Complementary therapies in medicine · 2024Trial
- Nurse-Administered Auricular Point Acupressure for Cancer-Related Pain.Integrative cancer therapiesTrial
- Acupuncture and Acupressure for Cancer Symptom Management: an Opinion Statement Based on Preliminary Evidence Mapping.Current treatment options in oncology · 2026Review
- Manual Massage Therapy for Neuropathic Pain: Clinical Evidence and Mechanistic Insights.Pain research & management · 2026Review
- Tailoring an auricular point acupressure self-management program for chronic pain: lessons learned from rural partners.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- A short-term mindfulness and auricular acupressure program for preoperative sleep fragmentation in patients with spinal metastases: a retrospective quasi-experimental study.Frontiers in psychiatry · 2026Article
- Effects of Swanson theory-based auricular acupressure on chemotherapy-induced peripheral neuropathy, and broader health-related outcomes in patients with breast cancer: A randomized controlled trial.Asia-Pacific journal of oncology nursing · 2025Article
- Sustainability of a Non-pharmacological, Self-Managed Intervention for Chronic Musculoskeletal Pain: 3-group Randomized Controlled Pilot Trial.Research square · 2024Article
- Adapting and Evaluating a Theory-Driven, Non-Pharmacological Intervention to Self-Manage Pain.Healthcare (Basel, Switzerland) · 2024Article
- A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol.PloS one · 2024Article
- Biological Correlates of the Effects of Auricular Point Acupressure on Pain.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2023Article
- Therapeutics for Chemotherapy-Induced Peripheral Neuropathy: Approaches with Natural Compounds from Traditional Eastern Medicine.Pharmaceutics · 2022Review
- Advances in imaging technologies for the assessment of peripheral neuropathies in rheumatoid arthritis.Rheumatology international · 2021Review
- Auricular Point Acupressure Combined with Compound Lidocaine Cream to Manage Arteriovenous Fistula Puncture Pain: A Multicenter Randomized Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Auricular Point Acupressure Smartphone Application to Manage Chronic Musculoskeletal Pain: A Longitudinal, One-Group, Open Pilot Trial.Global advances in health and medicine · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to investigate the dynamic brain activity following auricular point acupressure (APA) in chemotherapy-induced neuropathy (CIN).
methodsParticipants received 4 weeks of APA in an open-pilot trial with repeated observation. Along with the clinical self-reported CIN outcomes, objective outcomes were measured over the course of the treatment by physiological changes in pain sensory thresholds from quantitative sensory testing (QST) and repeated functional magnetic resonance imaging scans.
resultsAfter 4 weeks of APA, participants had reported clinically significant improvements (ie, ≥30%) in a reduction of CIN symptoms (including pain, numbness, tingling, and stiffness) in lower extremity stiffness (32%), reduced foot sensitivity (13%), and higher pain threshold (13%). Across the 11 intrinsic brain networks examined, there was a trend toward significance of the connectivity of the basal ganglia network (BGN) to the salience network (SAL), which was decreased pre-APA versus immediate-APA (effect size [ES] = 1.04,
conclusionThe changes in connectivity and activity within or between the ECN, SAL, and BGN from pre- to post-APA suggest ongoing alterations in brain functional connectivity following APA, particularly in the insula, anterior cingulate, and dorsolateral prefrontal cortices, which play significant roles in pain, memory, and cognitive function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.