Evidence map›Paper›PMID 32110442›Full record

ArticleCurrent health sciences journal

Association of QRS Complex Fragmentation with QT Interval Prolongation in Patients with Ischemic Heart Disease.

N J Aquino, O A Centurión, J M Torales, L M Miño, K E Scavenius, J F Alderete, J C Candia, L B García, C Cáceres, J E Martínez and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

N J AquinoCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
O A CenturiónCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
J M ToralesCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
L M MiñoCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
K E ScaveniusCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
J F AldereteCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
J C CandiaCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
L B GarcíaCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
C CáceresCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
J E MartínezCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
O A LoveraCardiology Department, Clinic Hospital, Faculty of Medical Sciences, Asunción National University (UNA), San Lorenzo, Paraguay.
Royal Institute and Observatory of the Spanish Navy · ESUniversidad Nacional de Asunción · PY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe fragmented QRS complex (FQRS) was found to be associated to malignant ventricular arrhythmias and sudden death in patients with hypertrophic cardiomyopathy and other entities. There is scant data available correlating the presence of FQRS with QT interval prolongation in patients with ischemic heart disease (IHD).

methodsA descriptive, retrospective, cross-sectional study was performed in 123 patients with IHD to analyze and correlate the presence of FQRS with QT interval prolongation in the conventional 12-leads electrocardiogram in patients with documented chronic IHD.

resultsThere were 62% male patients. The mean age was 63.8±12.6 years. Thirty six (44%) patients had fragmented QRS (64% men and 36% women). The duration of QT and QTc, the mean values were 413±59ms, and 463±67ms, respectively. Of the 36 patients with FQRS, 23 patients have prolongation of the QTc interval, and 13 patients did not present it. Of the 45 patients without FQRS, 21 of them have prolongation of the QTc interval, and 24 patients did not have it. These data resulted in a sensitivity of 52% with a moderate SnNout, a specificity of 65% with moderate SpPin, a positive predictive accuracy of 64%, a negative predictive accuracy of 53%. These data resulted in a prevalence of 54%.

conclusionthe presence of FQRS in the ECG has a moderate sensitivity and specificity, as well as, moderate negative and positive predictive value of the existence of QT interval prolongation in patients with ischemic heart disease.

Indexed as

Fragmented QRS complexischemic heart diseaseQT prolongation

Identifiers

PMID32110442
PMCPMC7014980
OpenAlexW3013832883

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.