Evidence map›Paper›PMID 32110321›Full record

ArticleChemical science2019

Microgel PAINT - nanoscopic polarity imaging of adaptive microgels without covalent labelling.

Ashvini Purohit, Silvia P Centeno, Sarah K Wypysek, Walter Richtering, Dominik Wöll

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashvini PurohitInstitute of Physical Chemistry , RWTH Aachen University , Landoltweg 2 , 52074 Aachen , Germany . Email: woell@pc.rwth-aachen.de.ORCID 0000-0002-4036-2490
Silvia P CentenoInstitute of Physical Chemistry , RWTH Aachen University , Landoltweg 2 , 52074 Aachen , Germany . Email: woell@pc.rwth-aachen.de.ORCID 0000-0002-5199-2121
Sarah K WypysekInstitute of Physical Chemistry , RWTH Aachen University , Landoltweg 2 , 52074 Aachen , Germany . Email: woell@pc.rwth-aachen.de.ORCID 0000-0001-6055-2374
Walter RichteringInstitute of Physical Chemistry , RWTH Aachen University , Landoltweg 2 , 52074 Aachen , Germany . Email: woell@pc.rwth-aachen.de.ORCID 0000-0003-4592-8171
Dominik WöllInstitute of Physical Chemistry , RWTH Aachen University , Landoltweg 2 , 52074 Aachen , Germany . Email: woell@pc.rwth-aachen.de.ORCID 0000-0001-5700-4182

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymer nanostructures have enormous potential for various applications in materials and life sciences. In order to exploit and understand their full capabilities, a detailed analysis of their structures and the environmental conditions in them is essential on the nanoscopic scale. With a super-resolution fluorescence microscopy technique known as PAINT (Points Accumulation for Imaging in Nanoscale Topography), we imaged colloidal hydrogel networks, so-called microgels, having a hydrodynamic radius smaller than the diffraction limit, gaining unprecedented insight into their full 3D structure which is not accessible in this much detail with any other experimental method. In addition to imaging of the microgel structure, the use of Nile Red as the solvatochromic fluorophore allowed us to resolve the polarity conditions within the investigated microgels, thus providing nanoscopic information on the

Identifiers

PMID32110321
PMCPMC6984396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.