Evidence map›Paper›PMID 32110225›Full record

ArticleCase reports in oncology

Rapidly Progressive Acute Kidney Injury Associated with Nivolumab Treatment.

Sachi Okawa, Keiichi Fujiwara, Atsushi Shimonishi, Hiroaki Matsuura, Taichi Ozeki, Jun Nishimura, Hiroe Kayatani, Daisuke Minami, Yoko Shinno, Ken Sato and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sachi OkawaDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Keiichi FujiwaraDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Atsushi ShimonishiDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Hiroaki MatsuuraDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Taichi OzekiDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Jun NishimuraDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Hiroe KayataniDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Daisuke MinamiDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Yoko ShinnoDepartment of Pathology, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Ken SatoDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Kosuke OtaDepartment of Nephrology, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Takuo ShibayamaDepartment of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Okayama Medical Center · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 63-year-old man with pulmonary adenocarcinoma was treated with nivolumab. High fever developed within several hours after the first administration of nivolumab; subsequently, serum creatinine levels kept increasing daily. We diagnosed acute kidney injury (AKI) as an immune-related adverse event; the patient was initially treated with 50 mg prednisolone, and the dose was then tapered. Renal biopsy pathologically revealed tubulointerstitial inflammation with strong infiltration of only T cells that were CD3

Indexed as

Acute kidney injuryAcute tubular necrosisImmune checkpoint inhibitorsNivolumabRenal biopsy

Identifiers

PMID32110225
PMCPMC7036533
OpenAlexW3004920236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.