Evidence map›Paper›PMID 32110215›Full record

ArticleCase reports in oncology

HPV-Related Neovaginal Squamous Cell Carcinoma Presenting as Lung Metastasis after Male-to-Female Gender Confirmation Surgery.

Gang Wang, David Ferguson, Diana N Ionescu, Lien Hoang, Sarah Barrett, Dirk van Niekerk, James Neil Rose, Christian Kollmannsberger

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Barriers and Facilitators to HPV Vaccination Completion among Transgender Women in Mexico: Implications for HPV Prevention and Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. A Case of a Transwoman with Colorectal Cancer after Flap Vaginoplasty.Journal of plastic and reconstructive surgery · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gang WangDepartment of Pathology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
David FergusonDepartment of Radiology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
Diana N IonescuDepartment of Pathology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
Lien HoangDepartment of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada.
Sarah BarrettDepartment of Radiology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
Dirk van NiekerkDepartment of Pathology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
James Neil RoseDepartment of Radiation Oncology, BC Cancer Abbotsford Centre, Abbotsford, British Columbia, Canada.
Christian KollmannsbergerDepartment of Medical Oncology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
University of British Columbia · CABC Cancer Agency · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There have been 4 reported cases of squamous cell carcinoma (SCC) of the neovagina in transgender women. In this report, we present another case of neovaginal SCC in a transgender woman, which was HPV-related, with lung metastasis as the initial presentation, and which was also complicated by her previous history of metastatic renal cell carcinoma. This unique case highlights the diagnostic challenges in these unusual scenarios. Through this report, we hope to address the benefits of multidisciplinary tumor board rounds, provision of detailed clinical information, and familiarization of the transgender anatomy within the pelvis in this group of patients. We also propose that transgender women undergo a continuous annual follow-up after postoperative follow-up is completed.

Indexed as

HPVMetastasisNeovaginaSquamous cell carcinomaTransgender

Identifiers

PMID32110215
PMCPMC7036568
OpenAlexW3001425224

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.