ArticleTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2020
Impact of Regular Whole-Blood Donation on Body Iron Stores.
Article in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- What is the impact of whole-blood donation frequency on donor health? A systematic review.Vox sanguinis · 2026Pooled it
- Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors.The Cochrane database of systematic reviews · 2026Pooled it
- Relationship of Genetic Variability (Health science reports · 2026Article
- Bioavailability of Functional Iron in Protein Microparticles.Nutrients · 2026Article
- Assessing Liver and Iron Markers in Steady State Pediatric SCD Patients to Ascertain the Hepatic Consequences of Hemotransfusion: A Case-Control Study in Ghana.Health science reports · 2026Article
- Impact of iron supplementation among anemic voluntary first-time blood donors: Results from the BLOODSAFE pilot trial in Ghana.Transfusion · 2025Article
- Evaluating utility of routine ferritin testing in blood donors: A hospital-based blood donor centre experience.Transfusion medicine (Oxford, England) · 2024Article
- Association of Early Hysterectomy With Risk of Cardiovascular Disease in Korean Women.JAMA network open · 2023Article
- Iron stores in steady-state sickle cell disease children accessing care at a sickle cell disease clinic in Kumasi, Ghana: A cross-sectional study.Health science reports · 2022Article
- Factors associated with serum ferritin levels and iron excess: results from the EPIC-EurGast study.European journal of nutrition · 2022Article
- Long-term Effects of Regular Whole Blood Donation on Peripheral Blood CD34Iranian journal of pathology · 2022Article
- Blood Donor Deferral Analysis in Relation to the Screening Process: A Single-Center Study from Southern India with Emphasis on High Hemoglobin Prevalence.Journal of blood medicine · 2020Article
- Iron supplementation and blood donation in Nigeria: Effect on Hemoglobin, red cell indices, and iron stores - The ranferon™ study.Annals of African medicineArticle
- Assessment of iron status in regular blood donors in a tertiary care hospital in Southern India.Asian journal of transfusion scienceArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesRegular and repeat blood donations may cause reduced body iron stores (BIS), which may lead to a shrinking donor pool. Furthermore, hemoglobin (Hb) itself is quite an inadequate measure to detect iron deficiency. Hence, our primary aim was to understand the effect of repeated blood donations on BIS in regular blood donors. STUDY DESIGN AND
settingWe conducted a prospective study on voluntary whole-blood donors (September 2015 through August 2017). Donor demographics were noted. Donors were further divided into four groups, depending on their number of donations. Their samples were tested for Hb, red cell indices, and serum ferritin to check for reduced BIS. The data obtained were analyzed using SPSS version 20 (IBM, USA).
resultsA total of 374 regular voluntary blood donors were included in the study. The mean serum ferritin levels in males and females were 75.4 and 36.2µg/L, respectively. There was a 45% decrement in the mean serum ferritin values in Group I (101.57 µg/L) in contrast to Group III (56.69 µg/L) (
conclusionThe present study demonstrates iron depletion in regular voluntary blood donors. In 11.2% of the donors, iron deficiency erythropoiesis was noted. A ferritin screening after the first donation followed up at the tenth donation might help detect iron-deficient individuals. Iron supplementation for all regular blood donors and female donors in particular will help prevent the shrinking donor pool due to iron deficiency.
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