ArticleJournal of experimental pharmacology2020
Antidiabetic Activity of Extracts of
Article in Journal of experimental pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Evaluation of the anti-hyperglycemic and anti-dyslipidemic potential of the hydroethanolic extract ofMetabolism open · 2026Article
- Ethnobotanical study of medicinal plants used to treat human and livestock ailments in Addi Arkay district, northwest Ethiopia.Journal of ethnobiology and ethnomedicine · 2025Article
- Article
- Antidiabetic Effects and Mechanisms of Action of Uncaria gambir Roxb. in Diabetic Sprague-Dawley Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Potential of Sorghum Seeds in Alleviating Hyperglycemia, Oxidative Stress, and Glycation Damage.Molecules (Basel, Switzerland) · 2024Article
- Evaluation of the Hypoglycemic and Hypolipidemic Potential of Extract Fraction ofCurrent pharmaceutical design · 2024Article
- Antimicrobial activity and enzymatic analysis of endophytes isolated from Codonopsis pilosula.FEMS microbiology ecology · 2023Article
- Article
- Article
- Quality Control, Anti-Hyperglycemic, and Anti-Inflammatory Assessment ofPlants (Basel, Switzerland) · 2022Article
- Pharmacological evaluation of medicinal plants with antidiabetic activities in Ethiopia: A review.Metabolism open · 2022Review
- The Glycemic Control Potential of Some Amaranthaceae Plants, with Particular Reference to In Vivo Antidiabetic Potential ofMolecules (Basel, Switzerland) · 2022Article
- Characterization of Possible α-Glucosidase Inhibitors fromPlants (Basel, Switzerland) · 2022Article
- Evaluation of Antidiabetic and Antihyperlipidemic Activity of 80% Methanolic Extract of the Root ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Antidiabetic Activity of Hydromethanolic Extract of CrudeJournal of experimental pharmacology · 2022Article
- Phytochemical Investigation and Therapeutical Potential ofOxidative medicine and cellular longevity · 2022Article
- Medicinal Plant Extracts EvaluatedEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Phytochemical Screening and Antidiabetic, Antihyperlipidemic, and Antioxidant Effects ofFrontiers in pharmacology · 2021Article
- Hypoglycemic, Anti-Hyperglycemic and Anti-Hyperlipidemic Effects ofJournal of experimental pharmacology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus is a chronic metabolic disorder that imposes a huge health and economic burden on societies. Because the currently available medications have many drawbacks, it is important to search for alternative therapies. Medicinal plants used in traditional medicines are ideal candidates. Hence, this study was undertaken to investigate the antidiabetic activity of crude extract and solvent fractions from the stem bark of MATERIALS AND
methodsThe in vitro α-amylase inhibition assay was performed using the chromogenic 3, 5-dinitrosalicylic acid (DNSA) method while the antihyperglycemic activity was assessed using three mouse models: streptozotocin-induced diabetic mice, normoglycemic mice, and oral glucose challenged mice. Experimental diabetes was induced by a single intraperitoneal injection of streptozotocin at a dose of 150 mg/kg and animals with fasting blood glucose level (BGL) >200 mg/dL were considered diabetic. Glibenclamide (5 mg/kg) was used as a standard drug. Fasting BGL and body weight were used to assess the antidiabetic activity. The result was analyzed using GraphPad Prism software version 8 and one-way ANOVA followed by Tukey's post hoc test with
resultsThe crude extract of
conclusion
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.