Evidence map›Paper›PMID 32110037›Full record

ArticleOncoTargets and therapy2020

Management of Ewing Sarcoma Family of Tumors: A Short Description of a Rare Primitive Uterine pPNET and Literature Review.

Salvatore Pisconti, Giuseppina Della Vittoria Scarpati, Carlo Buonerba, Simona Messinese, Roberta Carella, Massimiliano Di Marzo, Giuseppe Di Lorenzo, Grazia Lazzari, Francesco Perri, Raffaele Solla

Open access · goldAbstract readCase Reports
In one paragraph

Article in OncoTargets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Primary cutaneous extraskeletal Ewing sarcoma of the plantar region: clinicopathological features and review of the literature.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Salvatore PiscontiMedical Oncology Unit, POC, SS Annunziata, Taranto, Italy.
Giuseppina Della Vittoria ScarpatiMedical Oncology Unit, Pollena Trocchia Hospital, ASL NA3sud, Naples, Italy.
Carlo BuonerbaDepartment of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.ORCID 0000-0002-1806-442X
Simona MessineseMedical Oncology Unit, POC, SS Annunziata, Taranto, Italy.
Roberta CarellaMedical Oncology Unit, POC, SS Annunziata, Taranto, Italy.
Massimiliano Di MarzoDepartment of Abdominal Surgery, National Tumor Institute of Naples IRCCS G. Pascale, Naples, Italy.
Giuseppe Di LorenzoDepartment of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy.
Grazia LazzariDepartment of Radiation Oncology, POC, SS Annunziata, Taranto, Italy.ORCID 0000-0002-9137-2007
Francesco PerriHead and Neck Medical Oncology Unit, National Tumor Institute of Naples IRCCS G. Pascale, Naples, Italy.ORCID 0000-0001-8158-7509
Raffaele SollaDepartment of Radiation Oncology, University of Naples Federico II, Naples, Italy.ORCID 0000-0002-6515-9237
Ospedale SS. Annunziata · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of Naples Federico II · ITInstitute of Biostructure and Bioimaging · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the outcome of a patient with a rare primitive uterine pPNET and to perform a review of the available data in literature, leading the clinicians to better face this rare disease.

methodsWe have rescued data regarding the multidisciplinary treatment of pPNET from the PUBMED database, highlighting also issues regarding the pathogenesis and the genetic landscape of the ESFTs (Ewing Sarcoma Family of Tumors).

resultsEwing sarcoma and primitive neuroectodermal tumors (PNETs) are small round cell tumors presenting with different degrees of neuroectodermal differentiation. PNETs are further divided into central PNET and peripheral PNET (pPNET). Since pPNETs share the same genetic background of Ewing Sarcomas, they are considered to belong to the Ewing Sarcoma Family of Tumors (ESFTs). Multimodality treatment currently represents the best choice to offer to the affected patients.

conclusionAlthough pPNETs are generally diagnosed in children and young adults, an elderly woman aged 85 years came to our attention after a diagnosis of uterine pPNET. Her medical history is presented here, along with a literature review of the subject, highlighting the main biological, pathological and clinical features, with a hypothesis about the possible future therapeutic approaches for these rare malignancies.

Indexed as

Ewing SarcomageneticsPNETpPNET

Identifiers

PMID32110037
PMCPMC7034293
OpenAlexW3006512240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.