Evidence map›Paper›PMID 32110009›Full record

ArticleInternational journal of nanomedicine2020

Scolicidal Effects of Nanoparticles Against Hydatid Cyst Protoscolices in vitro.

Roghayeh Norouzi, Amin Ataei, Marzie Hejazy, Ayman Noreddin, Mohamed Ezzat El Zowalaty

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Propofol Induces the Expression of Nrf2 and HO-1 inTropical medicine and infectious disease · 2023
    Article
  9. Scolicidal effects ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  10. Article
  11. Review
  12. Biotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roghayeh NorouziDepartment of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Amin AtaeiDepartment of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Marzie HejazyDepartment of Basic Science, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Ayman NoreddinInfectious Diseases and Anti-Infective Therapy Research Group, Sharjah Medical Research Institute and College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0003-4899-1168
Mohamed Ezzat El ZowalatyDepartment of Pharmacy, City University College of Ajman, Ajman 18484, United Arab Emirates.ORCID 0000-0002-1056-4761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPURPOSE: The present study aimed to compare the scolicidal efficacies of silver, iron, copper, silica and zinc oxide nanoparticles (NPs) against hydatid cyst protoscolices in vitro.

methodsHydatid cysts of sheep liver and lung were collected. The cyst fluid containing protoscolices was aspirated aseptically. The scolicidal activities of the silver, iron, copper, silica and zinc nanoparticles (Ag-NP, Fe-NP, Cu-NP, Si-NP and Zn-NP) were tested at different concentrations of 0.25, 0.5 and 1 mg/mL following 10, 30 and 60 min of incubation in triplicate. Viability of protoscolices was confirmed by 0.1% eosin staining.

resultsResults showed that Ag-NPs at all concentrations tested had the highest scolicidal effect. Ag-NPs at 1 mg/mL concentration after 60 min of exposure time showed 80% mortality rate. Si-NPs had the high scolicidal activity at 1 mg/mL concentration (52.33%), Cu-NPs at 0.5 mg/mL concentration (41%), Fe-NPs at 1mg/mL concentration (28%) and Zn-NPs at concentration of 1mg/mL after 60 mins (15.67%).

conclusionThe findings of the present study showed that Ag-NPs, Fe-NPs, Cu-NPs, Si-NPs and Zn-NPs had potent scolicidal effects and that Ag-NPs are recommended as effective scolicidal agents. However, further in vivo studies are required to evaluate the efficacy of these nanoparticles.

Indexed as

AnimalsAnticestodal AgentsEchinococcosisEchinococcosis, HepaticEchinococcosis, PulmonaryEchinococcus granulosusMetal NanoparticlesSheepAnticestodal Agentscopper nanoparticlehydatid cystin vitroiron nanoparticleprotoscolicesscolicidalsilica nanoparticlesilver nanoparticle

Identifiers

PMID32110009
PMCPMC7034968

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.