Evidence map›Paper›PMID 32109562›Full record

ArticleThe ocular surface2020

Resident plasmacytoid dendritic cells patrol vessels in the naïve limbus and conjunctiva.

Arsia Jamali, Deshea L Harris, Tomas Blanco, Maria J Lopez, Pedram Hamrah

Open access · greenAbstract read
In one paragraph

Article in The ocular surface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Observational
  5. The impact of donor diabetes on corneal transplant immunity.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  6. Article
  7. Diurnal changes and topographical distribution of ocular surface epithelial dendritic cells in humans, and repeatability of density and morphology assessment.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Article
  8. Immune regulation of the ocular surface.Experimental eye research · 2022
    Review
  9. Review
  10. The Limbal Niche and Regenerative Strategies.Vision (Basel, Switzerland) · 2021
    Review
  11. Plasmacytoid dendritic cells in the eye.Progress in retinal and eye research · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arsia JamaliCenter for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Schepens Eye Research Institute/Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Deshea L HarrisCenter for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Schepens Eye Research Institute/Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Tomas BlancoCenter for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA.
Maria J LopezCenter for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Schepens Eye Research Institute/Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Pedram HamrahCenter for Translational Ocular Immunology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA; Schepens Eye Research Institute/Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA; Program in Immunology, School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA; Cornea Service, Tufts New England Eye Center, Boston, MA, USA. Electronic address: pedram.hamrah@tufts.edu.
Tufts University · US

Funding

Mechanisms of Corneal Neuro-Immune CrosstalkR01EY029602 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI Pedram Hamrah · 2018 to 2026
$3.6M
The role of plasmacytoid dendritic cells in corneal immunityR01EY022695 · NEI · TUFTS MEDICAL CENTER · PI HAMRAH, PEDRAM · 2013 to 2017
$2.4M
The role of plasmacytoid dendritic cells in ocular angiogenesisR01EY026963 · NEI · TUFTS MEDICAL CENTER · PI HAMRAH, PEDRAM · 2017 to 2020
$1.9M
NEI NIH HHS R01 EY022695NEI NIH HHS R01 EY026963NEI NIH HHS R01 EY029602
6 · The paper itself

Abstract

Plasmacytoid dendritic cells (pDCs) constitute a unique population of bone marrow-derived cells that play a pivotal role in linking innate and adaptive immune responses. While peripheral tissues are typically devoid of pDCs during steady state, few tissues do host resident pDCs. In the current study, we aim to assess presence and distribution of pDCs in naïve murine limbus and bulbar conjunctiva. Immunofluorescence staining followed by confocal microscopy revealed that the naïve bulbar conjunctiva of wild-type mice hosts CD45

Indexed as

ConjunctivaDendritic CellsEndothelial CellsAnimalsMiceMice, Inbred C57BLMice, TransgenicConjunctivaIntravital microscopyLimbusPlasmacytoid dendritic cellVascular endothelial cell

Identifiers

PMID32109562
PMCPMC7397780
OpenAlexW3008360869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.