Evidence map›Paper›PMID 32109430›Full record

ArticleContraception2020

Contraceptive use among women with cystic fibrosis: A pilot study linking reproductive health questions to the Cystic Fibrosis Foundation National Patient Registry.

Emily M Godfrey, Sheila Mody, Malaika R Schwartz, Sonya L Heltshe, Jennifer L Taylor-Cousar, Raksha Jain, Sandra Sufian, Tatiana Josephy, Moira L Aitken

Open access · greenAbstract read
In one paragraph

Article in Contraception, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Contraceptive use and pregnancy in cystic fibrosis: Survey findings from 10 cystic fibrosis centers.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Gynecologic health care for females with cystic fibrosis.Journal of clinical & translational endocrinology · 2021
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Emily M GodfreyDepartment of Family Medicine and Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA. Electronic address: godfreye@uw.edu.
Sheila ModyDivision of Family Planning, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, La Jolla, CA, USA.
Malaika R SchwartzDepartment of Family Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Sonya L HeltsheDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, University of Washington School of Medicine, Cystic Fibrosis Foundation Therapeutics Development Network, Seattle Children s Research Institute, Seattle, WA, USA.
Jennifer L Taylor-CousarDepartments of Medicine and Pediatrics, Divisions of Pulmonary, Critical Care and Sleep Medicine and Pediatric Pulmonary Medicine, National Jewish Health, Denver, CO, USA.
Raksha JainInternal Medicine, Pulmonary and Critical Care, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Sandra SufianDepartments of Medical Education and of Disability and Human Development, University of Illinois at Chicago College of Medicine and College of Applied Health Sciences, Chicago, IL, USA.
Tatiana JosephyDepartment of Family Medicine and Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA.
Moira L AitkenDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
University of Washington · USNational Jewish Health · USThe University of Texas Southwestern Medical Center · USUniversity of California San Diego · USUniversity of Illinois Chicago · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI PRADEEP k SINGH · 2010 to 2026
$21.4M
UC San Diego Womens Reproductive Health Research ProgramK12HD001259 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CYNTHIA GYAMFI-BANNERMAN · 1999 to 2026
$9.1M
NCATS NIH HHS UL1 TR002319NICHD NIH HHS K12 HD001259NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

objectivesTo examine contraceptive use, pregnancy intention and the association of hormonal contraceptive type with adverse health outcomes among women with cystic fibrosis (CF). STUDY

designWe recruited 150 women with CF, ages 18-49 from three adult CF programs to complete an online survey regarding their pregnancy and contraceptive use history. Survey findings were merged with retrospective clinical information from the CF Foundation Patient Registry (CFFPR). We used descriptive analyses to report contraceptive method and pregnancy frequencies, and logistic regression to examine the association between contraceptive method type and adverse health outcomes.

resultsCombined hormonal contraceptives were the most commonly used methods (42%), followed by condoms (34%), and long-acting reversible contraceptives methods (27%). Thirty-three percent (n = 50) reported ever being pregnant, half of whom reported having at least one unplanned pregnancy. We found no significant association for mucoid Pseudomonas aeruginosa infection among progestin-only (aOR 1.53, 95% CI 0.07-32.2) and estrogen-containing hormonal contraceptive users (aOR 3.9, 95 % CI 0.20-76.5). Risk of osteoporosis was elevated among women with CF who used depot-medroxyprogesterone acetate compared to non-users (OR 5.36, 95% CI 1.00-29.12).

conclusionsBoth contraceptive use and unplanned pregnancy among women with CF are common. Associations between hormonal contraceptive use and adverse pulmonary or bone outcomes among women with CF are inconclusive due to the study s small sample size. Larger studies are warranted. IMPLICATIONS: Women with CF should be informed about the risks and benefits of contraceptives in the context of their disease. CFFPR data capturing contraceptive method use may be the most efficient way to elucidate the association of hormonal contraceptives on disease in women with CF.

Indexed as

Pregnancy, UnplannedAdolescentAdultCondomsContraceptionContraception BehaviorContraceptives, Oral, HormonalCystic FibrosisFemaleHumansMiddle AgedPilot ProjectsPregnancyRegistriesReproductive HealthRetrospective StudiesContraceptives, Oral, HormonalContraceptionCystic fibrosisModulatorsPregnancyRegistryReproduction

Identifiers

PMID32109430
PMCPMC7494372
OpenAlexW3008152153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.