Evidence map›Paper›PMID 32109341›Full record

ArticlePhysiological reports2020

Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species-specific regulation of blood pressure.

Carlo J Mercado, Xiaochun Wang, Paul R Grimm, Paul A Welling, Yen-Pei C Chang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carlo J MercadoDivision of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
Xiaochun WangDivision of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
Paul R GrimmDepartments of Physiology and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Paul A WellingDepartments of Physiology and Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yen-Pei C ChangDivision of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-1998-6060
University of Maryland, Baltimore · USJohns Hopkins University · US

Funding

Genetic & Functional Analyses of Hypertension Susceptibility GenesR01HL088120 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI CHANG, YEN PEI CHRISTY · 2007 to 2017
$3.9M
Identification and Functional characterization of a gene influencing LDL-C on 5qR01HL121007 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2014 to 2017
$3.1M
NHLBI NIH HHS R01 HL088120NHLBI NIH HHS R01 HL121007NHLBI NIH HHS R01HL121007
6 · The paper itself

Abstract

STK39 encodes a serine threonine kinase, SPAK, which is part of a multi-kinase network that determines renal Na

Indexed as

AnimalsBlood PressureFemaleHEK293 CellsHeLa CellsHumansHypertensionKidneyMacaca mulattaMaleMiceMice, Inbred C57BLMiddle AgedMutationProtein IsoformsProtein Serine-Threonine KinasesProtein IsoformsProtein Serine-Threonine KinasesSodiumSTK39 protein, humanSTK39transcriptional regulation

Identifiers

PMID32109341
PMCPMC7048380
OpenAlexW3008132692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.