Evidence map›Paper›PMID 32109235›Full record

Trial reportScientific reports2020

Segmental Bioelectrical Impedance Spectroscopy to Monitor Fluid Status in Heart Failure.

Matthias Daniel Zink, Fabienne König, Sören Weyer, Klaus Willmes, Steffen Leonhardt, Nikolaus Marx, Andreas Napp

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. From ashes to insights: decoding water and electrolyte balance in colitis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthias Daniel ZinkDepartment of Cardiology, Angiology and Internal Intensive Care Medicine, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany. mzink@ukaachen.de.ORCID http://orcid.org/0000-0002-3889-5386
Fabienne KönigDepartment of Cardiology, Angiology and Internal Intensive Care Medicine, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
Sören WeyerChair for Medical Information Technology, RWTH Aachen University, Aachen, Germany.
Klaus WillmesDepartment of Neurology, University Hospital, RWTH Aachen University, Aachen, Germany.
Steffen LeonhardtChair for Medical Information Technology, RWTH Aachen University, Aachen, Germany.
Nikolaus MarxDepartment of Cardiology, Angiology and Internal Intensive Care Medicine, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
Andreas NappDepartment of Cardiology, Angiology and Internal Intensive Care Medicine, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0001-5329-6675
RWTH Aachen University · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioelectrical impedance spectroscopy (BIS) measures body composition, including fluid status. Acute decompensated heart failure (ADHF) is associated with fluid overload in different body compartments. This investigation aimed to evaluate the feasibility of measuring and monitoring fluid accumulation in patients with ADHF using BIS. The extracellular impedance as a surrogate marker for fluid accumulation was measured in 67 participants (25 healthy reference volunteers and 42 patients admitted with ADHF) using BIS in the "transthoracic", "foot-to-foot", "whole-body" and "hand-to-hand" segments. At baseline, BIS showed significantly lower extracellular resistance values for the "whole-body" (P < 0.001), "foot-to-foot" (P = 0.03), "hand-to-hand" (P < 0.001) and "transthoracic" (P = 0.014) segments in patients with ADHF than the reference cohort, revealing a specific pattern for peripheral, central and general fluid accumulation. The "foot-to-foot" (AUC = 0.8, P < 0.001) and "hand-to-hand" (AUC = 0.74, P = 0.04) segments indicated compartments of fluid accumulation with good prediction. During cardiac recompensation, BIS values changed significantly and were in line with routine parameters for monitoring ADHF. Mean bodyweight change per day correlated moderately to good with BIS values in the "whole-body" (r = -0.4), "foot-to-foot" (r = -0.8) and "transthoracic" (r = -0.4) segments. Based on our analysis, we conclude that measuring and monitoring fluid accumulation in ADHF using segmental BIS is feasible and correlates with clinical parameters during recompensation.

Indexed as

AgedAged, 80 and overBody FluidsCohort StudiesElectric ImpedanceFemaleHeart FailureHospitalizationHumansMaleMiddle AgedSpectrum Analysis

Identifiers

PMID32109235
PMCPMC7046702
OpenAlexW3010021400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.