Evidence map›Paper›PMID 32108740›Full record

ArticlePsychosomatic medicine2020

Pervasive Discrimination and Allostatic Load in African American and White Adults.

Miriam E Van Dyke, Nicole Kau'i Baumhofer, Natalie Slopen, Mahasin S Mujahid, Cheryl R Clark, David R Williams, Tené T Lewis

Abstract read
In one paragraph

Article in Psychosomatic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. SomaticCells · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miriam E Van DykeFrom the Department of Epidemiology (Van Dyke, Lewis), Rollins School of Public Health, Emory University, Atlanta, Georgia; Department of Native Hawaiian Health (Baumhofer), John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii; Department of Epidemiology and Biostatistics (Slopen), School of Public Health, University of Maryland, College Park, Maryland; Division of Epidemiology (Mujahid), School of Public Health, University of California at Berkeley, Berkeley, California; and Brigham and Women's Hospital (Clark), Harvard Medical School, and Department of Social and Behavioral Sciences (Williams), Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Nicole Kau'i Baumhofer
Natalie Slopen
Mahasin S Mujahid
Cheryl R Clark
David R Williams
Tené T Lewis

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
Multidisciplinary Research Training to Reduce Inequities in Cardiovascular HealthT32HL130025 · NHLBI · EMORY UNIVERSITY · PI Tené T Lewis, Viola Vaccarino · 2016 to 2026
$6.4M
Longitudinal Perspectives on Race and Health in MIDUS: Insights from MilwaukeeR01AG047154 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2015 to 2017
$1000k
Howard Hughes Medical InstituteNHLBI NIH HHS T32 HL130025NIA NIH HHS R01 AG047154NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

objectiveThis study aimed to examine associations among race, the accumulation of multiple forms of discriminatory experiences (i.e., "pervasive discrimination"), and allostatic load (AL) in African Americans and whites in midlife.

methodsUsing data collected in 2004 to 2006 from 226 African American and 978 white adults (57% female; mean [SD] age = 54.7 [0.11] years) in the Midlife in the United States II Biomarker Project, a pervasive discrimination score was created by combining three discrimination scales, and an AL score was created based on 24 biomarkers representing seven physiological systems. Linear regression models were conducted to examine the association between pervasive discrimination and AL, adjusting for demographics and medical, behavioral, and personality covariates. A race by pervasive discrimination interaction was also examined to determine whether associations varied by race.

resultsAfrican Americans had higher pervasive discrimination and AL scores than did whites. In models adjusted for demographics, socioeconomic status, medications, health behaviors, neuroticism, and negative affect, a pervasive discrimination score of 2 versus 0 was associated with a greater AL score (b = 0.30, SE = 0.07, p < .001). Although associations seemed to be stronger among African Americans as compared with whites, associations did not statistically differ by race.

conclusionsMore pervasive discrimination was related to greater multisystemic physiological dysregulation in a cohort of African American and white adults. Measuring discrimination by combining multiple forms of discriminatory experiences may be important for studying the health effects of discrimination.

Indexed as

AdultAllostasisBiomarkersBlack or African AmericanCohort StudiesFemaleHealth BehaviorHealth Status DisparitiesHumansMaleMiddle AgedRacismSelf ReportSocial ClassStress, PsychologicalUnited StatesBiomarkers

Identifiers

PMID32108740
PMCPMC7138744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.