Evidence map›Paper›PMID 32108435›Full record

ArticleObesity (Silver Spring, Md.)2020

BMI Trajectories from Birth to 23 Years by Cardiometabolic Risks in Young Adulthood.

Patricia East, Erin Delker, Estela Blanco, Betsy Lozoff, Paulina Correa, Raquel Burrows, Sheila Gahagan

Open access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Obesity in Preschool Children Should Be Taken Seriously.Acta paediatrica (Oslo, Norway : 1992) · 2026
    Article
  4. Childhood obesity: The threatening apprentice of the adiposity empire.Reviews in endocrine & metabolic disorders · 2025
    Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Patricia EastDepartment of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0002-5169-2735
Erin DelkerDepartment of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA.
Estela BlancoDepartment of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA.
Betsy LozoffDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Paulina CorreaInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Raquel BurrowsInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.ORCID 0000-0001-9155-0689
Sheila GahaganDepartment of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0002-1105-7323
University of California San Diego · USUniversity of Chile · CLUniversity of Michigan · US

Funding

NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTSR01HD033487 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA, LOZOFF, BETSY · 1997 to 2016
$8.8M
UCSD Integrated Cardiovascular Epidemiology FellowshipT32HL079891 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew A Allison · 2007 to 2026
$6.7M
Biopsychosocial Determinants of Adolescent Obesity/Cardiovascular RiskR01HL088530 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA · 2008 to 2017
$5.0M
Long-Term Cognitive and Behavioral Effects of Early-Life Iron Deficiency and High-Iron SupplementationR03HD097295 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EAST, PATRICIA L · 2019 to 2020
$126k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R03-HD-097295NHLBI NIH HHS R01-HD-033487NHLBI NIH HHS R01 HL088530NHLBI NIH HHS R01-HL-088530NHLBI NIH HHS T32 HL079891NHLBI NIH HHS T32-HL-079891NICHD NIH HHS R01 HD033487NICHD NIH HHS R03 HD097295NIH HHS
6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate whether the level, rate, and acceleration of BMI growth differ according to the presence or absence of adult cardiometabolic (CM) risks.

methodsBMI was measured in 1,000 Chileans at nine time points from birth to 23 years, and metabolic syndrome and its components were assessed at young adulthood. BMI growth was analyzed in the following three developmental periods: birth to 6 months, 6 months to 5 years, and 5 to 23 years.

resultsIndividuals with CM risks had a specific constellation of early-life growth (faster growth after infancy, lower BMI decline approaching age 5, absence of a definitive BMI nadir in early childhood, higher 5-year BMI) and distinct young adult growth (larger BMI increases from childhood to young adulthood and lower levels of expected growth deceleration approaching young adulthood). Those with CM risks also attained BMI ≥ 25 at significantly younger ages than those absent risks (metabolic syndrome: 12.3 years vs. 20.1 years; hyperglycemia: 13.1 years vs. 18.9 years; hypertension: 13.2 years vs. 19.4 years; hypertriglyceridemia: 14.3 years vs. 19.5 years; inflammation: 15.9 years vs. 20.6 years).

conclusionsLarger and faster increases in BMI and a failure of BMI growth to decline or decelerate at specific developmental periods distinguished individuals who would and would not have adult CM risks.

Indexed as

Body Mass IndexAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMetabolic SyndromePregnancyRisk FactorsYoung Adult

Identifiers

PMID32108435
PMCPMC7093235
OpenAlexW3008758037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.