ArticleScientific reports2020
Psychological stress, cognitive decline and the development of dementia in amnestic mild cognitive impairment.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Association of Self-Reported Psychological Stress with Cognitive Decline: A Systematic Review.Neuropsychology review · 2023Pooled it
- Pooled it
- Cognitive Reserve and Psychological Well-Being in Aging Population of Community-Dwellers in Spain.Brain and behavior · 2026Article
- Physical activity and psychosocial profiles associated with mental health risk in community-dwelling older adults: a cross-sectional study.Frontiers in sports and active living · 2026Article
- The influence mechanism of mindfulness training on college students' psychological stress regulation: a mediation model with moderating effect.Frontiers in public health · 2026Article
- Psychosocial stressors and cognitive function: An analysis using data from the English longitudinal study of ageing.The journal of prevention of Alzheimer's disease · 2025Article
- The association between maternal stress and human milk concentrations of cortisol and prolactin.Scientific reports · 2024Article
- Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- The relationship between the diagnostic value of salivary cortisol levels and behavioral symptoms in patients with Alzheimer's disease.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2024Article
- Article
- Relationship between perceived social support and mental health among Chinese college football athletes: a moderated mediation model.BMC psychology · 2023Article
- Stress, depression, and risk of dementia - a cohort study in the total population between 18 and 65 years old in Region Stockholm.Alzheimer's research & therapy · 2023Article
- Novel Combination of Choline withInternational journal of molecular sciences · 2023Article
- Prevalence of suspected dementia in a sample of adults living in Kinshasa-Democratic Republic of the Congo.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Association of stressful life events with cognitive impairment in patients with type 2 diabetes mellitus.Journal of diabetes investigation · 2023Article
- The longitudinal relationship between hearing loss and cognitive decline in tonal language-speaking older adults in China.Frontiers in aging neuroscience · 2023Article
- Understanding the relationships between physiological and psychosocial stress, cortisol and cognition.Frontiers in endocrinology · 2023Review
- Associations between self-reported psychological symptom severity and gut microbiota: further support for the microgenderome.BMC psychiatry · 2022Article
- Association between symptoms of psychological distress and cognitive functioning among adults with coronary artery disease.Stress and health : journal of the International Society for the Investigation of Stress · 2021Article
- Psychosocial Stress Hastens Disease Progression and Sudden Death in Mice with Arrhythmogenic Cardiomyopathy.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 2 countries.
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Abstract
To determine the relationship between psychological stress with cognitive outcomes in a multi-centre longitudinal study of people with amnestic mild cognitive impairment (aMCI) we assessed three parameters of psychological stress (Recent Life Changes Questionnaire (RLCQ); the Perceived Stress Scale (PSS) and salivary cortisol) and their relationship with rates of cognitive decline over an 18 month follow up period and conversion to dementia over a 5.5 year period. In 133 aMCI and 68 cognitively intact participants the PSS score was higher in the aMCI compared with control group but neither the RLCQ scores nor salivary cortisol measures were different between groups. In the aMCI group the RLCQ and the PSS showed no significant association with cognitive function at baseline, cognitive decline or with conversion rates to dementia but high salivary cortisol levels were associated with RLCQ scores and poorer cognitive function at baseline and lower rates of cognitive decline. No relationship was found between salivary cortisol levels and conversion rate to dementia. We conclude that psychological stress as measured by the RLCQ or PSS was not associated with adverse cognitive outcomes in an aMCI population and hypothesise that this may reflect diminished cortisol production to psychological stress as the disease progresses.
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