Evidence map›Paper›PMID 32107772›Full record

ArticleThe British journal of dermatology2020

Measurement properties of the Patient-Reported Outcomes Information System (PROMIS

J I Silverberg, J-S Lai, K R Patel, V Singam, P P Vakharia, R Chopra, R Sacotte, R Kantor, D Y Hsu, D Cella

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In one paragraph

Article in The British journal of dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Prevalence and associations of fatigue in childhood atopic dermatitis: A cross-sectional study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Observational
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Observational
  18. Article
  19. How to measure itch in atopic dermatitis?The British journal of dermatology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

J I SilverbergDepartment of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.ORCID 0000-0003-3686-7805
J-S LaiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-1840-2537
K R PatelDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-3440-7493
V SingamDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-9502-8828
P P VakhariaDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-7945-0981
R ChopraDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-8150-6358
R SacotteDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0001-9776-8670
R KantorDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0001-7870-3791
D Y HsuDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
D CellaDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-9881-4541
Northwestern University · US

Funding

Northwestern University Patient-centered Intervention and Engagement TrainingK12HS023011 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2014 to 2018
$3.7M
AHRQ HHS K12 HS023011Dermatology FoundationGalderma
6 · The paper itself

Abstract

backgroundLittle is known about the validity of numeric rating scales (NRS) and verbal rating scales (VRS) for itch and itch frequency for assessing itch severity in atopic dermatitis (AD). We evaluated the Patient-Reported Outcomes Information System (PROMIS

methodsSelf-administered questionnaires and skin examinations were performed in 410 patients with AD (aged 18-90 years) in a dermatology practice setting.

resultsPIQ NRS, VRS and frequency of itch had good content validity, strong correlations with one another (Spearman correlations P < 0·001) and weak-to-moderate correlations with patient-oriented eczema measure (POEM), Eczema Area and Severity Index (EASI), objective SCORing AD (SCORAD) and Dermatology Life Quality Index (DLQI) (P < 0·001) and very good discriminant validity. Changes from baseline in NRS, VRS and frequency of itch were moderately to strongly correlated with one another, and weakly to moderately correlated with other patient-reported (POEM, SCORAD itch, DLQI) and clinician-reported outcomes (EASI, objective SCORAD). NRS and VRS worst itch and average itch showed moderate-to-good test-retest reliability. There were no floor or ceiling effects for NRS or VRS itch, but there were ceiling effects for itch frequency. Each assessment was completed in < 1 min by all patients.

conclusionsNRS, VRS and frequency of itch items from PIQ - itch severity showed good content and construct validity, reliability, and/or responsiveness in adults with AD, and were feasible for use in clinical trials and practice. What is already known about this topic? Numeric rating scales (NRS), verbal rating scales (VRS) and frequency of itch have been used to assess the burden of itch. However, there have been limited results demonstrating their validity, responsiveness, interpretability and feasibility, particularly in atopic dermatitis (AD). What does this study add? This study demonstrated that NRS, VRS and frequency of itch items from the Patient-Reported Outcomes Information System (PROMIS

Indexed as

Dermatitis, AtopicEczemaAdolescentAdultAgedAged, 80 and overHumansInformation SystemsMiddle AgedPatient Reported Outcome MeasuresReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesYoung Adult

Identifiers

PMID32107772
OpenAlexW3024220876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.