Evidence map›Paper›PMID 32107678›Full record

ReviewDigestive diseases and sciences2020

Early Liver Transplantation for Severe Alcoholic Hepatitis.

Jessica L Mellinger, Jonathan G Stine

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. [Progress in the clinical treatment of alcoholic hepatitis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jessica L MellingerDivision of Gastroenterology and Hepatology, Department of Medicine, The University of Michigan, Ann Arbor, MI, USA.
Jonathan G StineDivision of Gastroenterology and Hepatology, Department of Medicine, The Pennsylvania State University- Milton S. Hershey Medical Center, Hershey, PA, 17033, USA. jstine@pennstatehealth.psu.edu.
Penn State Milton S. Hershey Medical Center · USUniversity of Michigan–Ann Arbor · US

Funding

Improving Outcomes in Alcoholic Liver Disease: Integrating Behavioral Interventions into the Hepatology ClinicK23AA026333 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MELLINGER, JESSICA LEIGH · 2018 to 2022
$972k
NIAAA NIH HHS K23 AA026333NIDDK NIH HHS L30 DK118601
6 · The paper itself

Abstract

Although alcohol-associated liver disease has long been a major component of the liver disease landscape, it was overshadowed by chronic hepatitis C until recently. Nevertheless, with the declining incidence of hepatitis C in the wake of highly effective antiviral therapy, attention has shifted to the increasing burden of alcohol-associated liver disease. The incidence of advanced alcohol-associated liver disease, including acute alcoholic hepatitis and alcohol-associated cirrhosis, is rising in parallel with increasing rates of alcohol use disorders. As a result, alcohol-associated liver disease is now one of the most common indications for liver transplantation. Rates of liver transplantation for acute alcoholic hepatitis are rising as well in spite of the sparse guidance regarding candidate selection, counseling, postoperative care, long-term follow-up, and other best practices. To this day, liver transplant for acute alcoholic hepatitis remains a hotly debated clinical controversy.

Indexed as

Liver TransplantationAlcoholismFemaleGraft SurvivalHepatitis, AlcoholicHumansLiver Cirrhosis, AlcoholicLiver Diseases, AlcoholicMalePatient SelectionTreatment OutcomeAlcohol-related liver diseaseAlcohol use disorderCirrhosisRelapse

Identifiers

PMID32107678
PMCPMC7230003
OpenAlexW3008616470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.