Evidence map›Paper›PMID 32107627›Full record

ArticleCurrent microbiology2020

Phytochemical Screening and Detection of Antibacterial Components from Crude Extracts of Some Armenian Herbs Using TLC-Bioautographic Technique.

Mikayel Ginovyan, Arpine Ayvazyan, Armine Nikoyan, Lilit Tumanyan, Armen Trchounian

Abstract read
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In one paragraph

Article in Current microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Traditionally Used Medicinal Plants of Armenia.Plants (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. StandardizedAntioxidants (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Antibiotics (Basel, Switzerland) · 2022
    Article
  13. Review
  14. A comprehensive review ofFrontiers in pharmacology · 2022
    Review
  15. A Comprehensive Review of GenusFrontiers in pharmacology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mikayel GinovyanDepartment of Biochemistry, Microbiology and Biotechnology, Yerevan State University, 1 A. Manoogian Str, 0025, Yerevan, Armenia.ORCID http://orcid.org/0000-0002-8585-5539
Arpine AyvazyanDepartment of Biochemistry, Microbiology and Biotechnology, Yerevan State University, 1 A. Manoogian Str, 0025, Yerevan, Armenia.
Armine NikoyanDepartment of Biochemistry, Microbiology and Biotechnology, Yerevan State University, 1 A. Manoogian Str, 0025, Yerevan, Armenia.
Lilit TumanyanDepartment of Biochemistry, Microbiology and Biotechnology, Yerevan State University, 1 A. Manoogian Str, 0025, Yerevan, Armenia.
Armen TrchounianDepartment of Biochemistry, Microbiology and Biotechnology, Yerevan State University, 1 A. Manoogian Str, 0025, Yerevan, Armenia. Trchounian@ysu.am.
Yerevan State University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the research was to explore qualitative and quantitative phytochemical constituents of different extracts from Agrimonia eupatoria L., Hypericum alpestre subsp. polygonifolium (Rupr.) Avet. & Takht., Rumex obtusifolius Willd and Sanguisorba officinalis L. and analyze their bioactive constituents using TLC-bioautography technique. In TLC analysis different solvent systems as mobile phases were used in order to make assumptions about the nature of active antibacterial compounds. The highest total phenolic, flavonoid and tannin content was detected in methanol extract of A. eupatoria (358.9 µg Gallic acid equivalent per mg dry weight), acetone extract of H. alpestre (216.75 µg Quercetin equivalent per mg dry weight) and acetone extract of R. obtusifolius (76.24 µg Catechin equivalent per mg dry weight), respectively. TLC-bioautography analysis using mobile phases with different polarity allowed to separate different bands from tested plants methanol and acetone extracts possessing antibacterial activity against Staphylococcus aureus MDC 5233. Thus, it was revealed, that polar compounds could have considerable contribution to the antibacterial activity of acetone and methanol extracts of H. alpestre and R. obtusifolius. It was hypothesized, that complex compounds can be responsible for the antibacterial action of extracts of A. eupatoria and S. officinalis. Based on obtained data, A. eupatoria, H. alpestre, R. obtusifolius and S. officinalis plants can be recommended as sources of new antibacterial agents.

Indexed as

Anti-Bacterial AgentsPhytochemicalsArmeniaChromatography, Thin LayerMagnoliopsidaPlant ExtractsStaphylococcus aureusAnti-Bacterial AgentsPhytochemicalsPlant Extracts

Identifiers

PMID32107627
OpenAlexW3006847434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.