Evidence map›Paper›PMID 32107573›Full record

ArticleAnalytical and bioanalytical chemistry2020

In situ metabolite and lipid analysis of GluN2D

William T Andrews, Deborah Donahue, Adam Holmes, Rashna Balsara, Francis J Castellino, Amanda B Hummon

Open access · greenAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Spatial regulation effects of Taohong Siwu decoction on disordered lipids in a rat model of ischemic stroke assessed using mass spectrometry imaging.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

William T AndrewsDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Cavanaugh Dr, Notre Dame, IN, 46556, USA. wandrew3@nd.edu.
Deborah DonahueDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Cavanaugh Dr, Notre Dame, IN, 46556, USA.
Adam HolmesDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Cavanaugh Dr, Notre Dame, IN, 46556, USA.
Rashna BalsaraDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Cavanaugh Dr, Notre Dame, IN, 46556, USA.
Francis J CastellinoDepartment of Chemistry and Biochemistry, University of Notre Dame, 236 Cavanaugh Dr, Notre Dame, IN, 46556, USA.
Amanda B HummonDepartment of Chemistry and Biochemistry and the Comprehensive Cancer Center, The Ohio State University, 414 Biomedical Research Tower, 460 W 12th Ave, Columbus, OH, 43210, USA. hummon.1@osu.edu.
University of Notre Dame · USThe Ohio State University · US

Funding

Spatial SILAC: Examining the Proteome in 3D Cell CulturesR01GM110406 · NIGMS · UNIVERSITY OF NOTRE DAME · PI HUMMON, AMANDA B. · 2014 to 2022
$3.0M
15 Tesla Bruker solariX FTICR MSS10OD018507 · OD · OHIO STATE UNIVERSITY · PI WYSOCKI, VICKI H. · 2014 to 2014
$2.0M
Electroblotting through enzymatic membranes to enhance MALDI tissue imaging of proteinsR21AG062144 · NIA · OHIO STATE UNIVERSITY · PI HUMMON, AMANDA B. · 2019 to 2020
$424k
NIA NIH HHS R21 AG062144NIA NIH HHS R21-AG062144NIGMS NIH HHS R01 GM110406NIGMS NIH HHS S10 OD018507NIH HHS S10 OD018507
6 · The paper itself

Abstract

The N-methyl-D-aspartate (NMDA) receptor is a crucial mediator of pathological glutamate-driven excitotoxicity and subsequent neuronal death in acute ischemic stroke. Although the roles of the NMDAR's composite GluN2A-C subunits have been investigated in this phenomenon, the relative importance of the GluN2D subunit has yet to be evaluated. Herein, GluN2D

Indexed as

Lipid MetabolismMetabolomeAnimalsBrainGene DeletionHumansIschemic StrokeLipidsMaleMice, Inbred C57BLMice, KnockoutReceptors, N-Methyl-D-AspartateSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationGrin2d protein, mouseLipidsReceptors, N-Methyl-D-AspartateBioanalytical methodsImagingMass spectrometry

Identifiers

PMID32107573
PMCPMC7483268
OpenAlexW3007238127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.