Evidence map›Paper›PMID 32107397›Full record

ArticleScientific reports2020

Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation.

Aldino Viegas, Peter Dollinger, Neha Verma, Jakub Kubiak, Thibault Viennet, Claus A M Seidel, Holger Gohlke, Manuel Etzkorn, Filip Kovacic, Karl-Erich Jaeger

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Virulence Factors ofFrontiers in cellular and infection microbiology · 2022
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Aldino Viegas *Institute of Physical Biology, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Peter Dollinger *Institute of Molecular Enzyme Technology, Heinrich Heine University Düsseldorf, 52425, Jülich, Germany.
Neha Verma *Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Jakub KubiakInstitute of Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Thibault ViennetInstitute of Physical Biology, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Claus A M SeidelInstitute of Molecular Physical Chemistry, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany. gohlke@uni-duesseldorf.de.
Manuel EtzkornInstitute of Physical Biology, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany. manuel.etzkorn@hhu.de.
Filip KovacicInstitute of Molecular Enzyme Technology, Heinrich Heine University Düsseldorf, 52425, Jülich, Germany.
Karl-Erich JaegerInstitute of Molecular Enzyme Technology, Heinrich Heine University Düsseldorf, 52425, Jülich, Germany. karl-erich.jaeger@fz-juelich.de.
Heinrich Heine University Düsseldorf · DEForschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folding and cellular localization of many proteins of Gram-negative bacteria rely on a network of chaperones and secretion systems. Among them is the lipase-specific foldase Lif, a membrane-bound steric chaperone that tightly binds (K

Indexed as

Bacterial ProteinsKineticsLipaseMolecular Dynamics SimulationProtein BindingProtein DomainsProtein FoldingPseudomonas aeruginosaBacterial ProteinsLipaselipase foldase

Identifiers

PMID32107397
PMCPMC7046727
OpenAlexW3010504757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.