ReviewThe British journal of ophthalmology2020
Optical coherence tomography-based consensus definition for lamellar macular hole.
Review in The British journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05747144 (Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies), which is not on this map. Cited by 90 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies: Biomarkers of Morpho-Functional Recovery by Artificial Intelligence
Who cites it
90 citing papers in PubMed, 3 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- SURGICAL OUTCOMES OF LAMELLAR MACULAR HOLE EYES WITH OR WITHOUT PRESERVATION OF LAMELLAR HOLE-ASSOCIATED EPIRETINAL PROLIFERATION TECHNIQUE: A Meta-analysis.Retina (Philadelphia, Pa.) · 2025Pooled it
- Surgical interventions for lamellar macular holes.The Cochrane database of systematic reviews · 2021Pooled it
- Primary vitrectomy for degenerative and tractional lamellar macular holes: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Visual and OCT outcomes in epiretinal membrane foveoschisis with and without lamellar macular hole-related diseases.Japanese journal of ophthalmology · 2026Article
- Intraretinal Hyperreflective Foci as an OCT Feature Associated With Retinal Remodeling After Macular Hole Closure.Investigative ophthalmology & visual science · 2026Article
- Evaluating ERM Stage and DRIL as predictive biomarkers for functional outcomes after iERM surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Multimodal imaging of photoreceptor and vascular changes in lamellar macular hole and epiretinal membrane-associated foveoschisis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Extended follow-up of ultrastructural remodeling and functional recovery after lamellar macular hole surgery using autologous platelet-rich plasma.Scientific reports · 2026Article
- EPIRETINAL PROLIFERATION EMBEDDING WITHOUT INTERNAL LIMITING MEMBRANE PEELING FOR LAMELLAR MACULAR HOLE.Retina (Philadelphia, Pa.) · 2026Article
- Macular Pigment Optical Density Levels Reflect Retinal Remodeling in Lamellar Macular Holes.Investigative ophthalmology & visual science · 2026Observational
- Morphological plasticity and visual acuity in the natural course of epiretinal membrane-foveoschisis: A longitudinal OCT study.Eye (London, England) · 2026Article
- Parafoveal retinal function of epiretinal membrane foveoschisis: a pilot comparison among ERM phenotypes using MP-3 microperimetry.BMC ophthalmology · 2026Article
- 3D volumetric analysis outperforms 2D linear measurements in predicting vision after surgery for epiretinal membranes. An exploratory machine learning study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Epiretinal proliferation around full-thickness macular holes- intrasurgical visualization of the whole size with membrane blue dual.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Neurosymbolic AI Framework for Explainable Retinal Disease Classification From OCT Images.Translational vision science & technology · 2026Article
- Atypical Epiretinal Proliferation in a Case of Tuberculosis Uveitis.Case reports in ophthalmological medicine · 2026Article
- Combined versus Sequential Surgery in Lamellar Macular Holes: A Multicenter Observational Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Changes in visual acuity and retinal microstructures following vitrectomy for lamellar macular hole.PloS one · 2026Article
- Epiretinal membrane peeling in eyes with pseudophakia: prognostic and morphological factors of visual outcomes.BMC ophthalmology · 2025Article
- Peeling of secondary epiretinal membrane in uveitis-functional improvement to be expected?International journal of retina and vitreous · 2025Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors at 12 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA consensus on an optical coherence tomography definition of lamellar macular hole (LMH) and similar conditions is needed.
methodsThe panel reviewed relevant peer-reviewed literature to reach an accord on LMH definition and to differentiate LMH from other similar conditions.
resultsThe panel reached a consensus on the definition of three clinical entities: LMH, epiretinal membrane (ERM) foveoschisis and macular pseudohole (MPH). LMH definition is based on three mandatory criteria and three optional anatomical features. The three mandatory criteria are the presence of irregular foveal contour, the presence of a foveal cavity with undermined edges and the apparent loss of foveal tissue. Optional anatomical features include the presence of epiretinal proliferation, the presence of a central foveal bump and the disruption of the ellipsoid zone. ERM foveoschisis definition is based on two mandatory criteria: the presence of ERM and the presence of schisis at the level of Henle's fibre layer. Three optional anatomical features can also be present: the presence of microcystoid spaces in the inner nuclear layer (INL), an increase of retinal thickness and the presence of retinal wrinkling. MPH definition is based on three mandatory criteria and two optional anatomical features. Mandatory criteria include the presence of a foveal sparing ERM, the presence of a steepened foveal profile and an increased central retinal thickness. Optional anatomical features are the presence of microcystoid spaces in the INL and a normal retinal thickness.
conclusionsThe use of the proposed definitions may provide uniform language for clinicians and future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.