Evidence map›Paper›PMID 32106864›Full record

ArticleBMC infectious diseases2020

Undiagnosed HIV, hepatitis B, and hepatitis C infections in people with severe psychiatric disorders in Ethiopia.

Getinet Ayano, Kibrom Haile, Abel Tesfaye, Kelemua Haile, Sileshi Demelash, Mikias Tulu, Belachew Tsegaye, Melat Solomon, Alem Kebede, Aynalem Biru and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 3 countries.

Getinet AyanoResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia. babiget2015@gmail.com.ORCID http://orcid.org/0000-0002-9137-4141
Kibrom HaileResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Abel TesfayeResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Kelemua HaileResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Sileshi DemelashEthiopian public health institute, Addis Ababa, Ethiopia.
Mikias TuluResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Belachew TsegayeResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Melat SolomonResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Alem KebedeResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Aynalem BiruResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Habte BirhanuResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Gebresilassie ZenawiResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Yodit HabtamuResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Esias KibronResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Seneshet EshetuResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Meseret SefiwResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Dawit AssefaResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Zegeye YohannesResearch and Training Department, Amanuel Mental Specialized Hospital, PO Box 171, Addis Ababa, Ethiopia.
Curtin University · AUEthiopian Public Health Institute · ETHawassa University · ET

Funding

Amanuel Mental Specialized Hospital --
6 · The paper itself

Abstract

backgroundWorldwide, there is limited epidemiologic evidence on the seroprevalence of undiagnosed chronic viral infections including HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among patients with severe psychiatric disorders. To our knowledge, this is the first study to explore and compare undiagnosed seroprevalence rates of HIV, HBV, and HCV infections among patients with severe psychiatric disorders.

methodIn this study, we included a random sample of 309 patients with severe psychiatric disorders selected by systematic sampling technique. We used a structured clinical interview for DSM-IV (SCID) to confirm the diagnosis of severe psychiatric disorders among the participants. Binary and multivariable logistic regression models, adjusting for the potential confounding factors was used to explore the potential determinants of chronic viral infections.

resultThe prevalence estimates of HIV infection among patients with severe psychiatric disorders in this study (3.24%) was roughly 3 times the estimated population prevalence of HIV infection in Ethiopia (1.1%). This study showed that the prevalence rates of HBV and HCV infections among patients with severe psychiatric disorders were 4.85 and 1.29%, respectively. Our results also showed that among patients with chronic viral infections, HIV, HBV and HCV, 76.92, 60, 80, and 75% respectively were undiagnosed. Regarding associated factors, the presence of chronic viral infection was found to be significantly associated with the age of the participants (ranging between 30 and 40 years) after adjusting for the possible confounding factors [AOR = 3.95 (95%CI.18-13.17)].

conclusionEven though the prevalence estimates of HIV (3.24%), HBV (4.85%), and HCV (1.29%) infections were high among patients with severe psychiatric disorders, the majority of them remained undiagnosed. HBV was found to be the commonly undiagnosed infection (4 out of 5) followed by HCV (3 out of 4) and HIV (6 out of 10). The present study provided evidence of a significant association between the age of the participant (between 30 and 40 years) and chronic viral infections in patients with severe psychiatric disorders. Increasing the awareness of psychiatry professionals and early screening, as well as interventions of chronic viral infections among patients with severe psychiatric disorders are imperative.

Indexed as

AdultCross-Sectional StudiesEthiopiaFemaleHepatitis BHepatitis CHIV InfectionsHumansLogistic ModelsMaleMental DisordersPrevalenceSeverity of Illness IndexAnd HCV infectionHBV infectionHIV infectionSevere psychiatric disorderUndiagnosed

Identifiers

PMID32106864
PMCPMC7045486
OpenAlexW3012805696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.