Evidence map›Paper›PMID 32106839›Full record

ArticleBMC pulmonary medicine2020

Restrictive spirometric pattern and true pulmonary restriction in a general population sample aged 50 - 64 years.

Kjell Torén, Linus Schiöler, Jonas Brisman, Andrei Malinovschi, Anna-Carin Olin, Göran Bergström, Björn Bake

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  5. Associations of Prepandemic Lung Function and Structure with COVID-19 Outcomes: The C4R Study.American journal of respiratory and critical care medicine · 2025
    Article
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  8. Review
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  11. Article
  12. Article
  13. Observational
  14. Article
  15. The ratio FEVClinical physiology and functional imaging · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kjell TorénOccupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414, S-405 30, Gothenburg, Sweden. Kjell.Toren@amm.gu.se.ORCID http://orcid.org/0000-0001-8509-7603
Linus SchiölerOccupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414, S-405 30, Gothenburg, Sweden.
Jonas BrismanDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Andrei MalinovschiDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Anna-Carin OlinOccupational and Environmental Medicine, School of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414, S-405 30, Gothenburg, Sweden.
Göran BergströmDepartment of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Björn BakeDepartment of Medicine/Lung Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

FORTE 2018Hjärt-Lungfonden 2018
6 · The paper itself

Abstract

backgroundThere is low diagnostic accuracy of the proxy restrictive spirometric pattern (RSP) to identify true pulmonary restriction. This knowledge is based on patients referred for spirometry and total lung volume determination by plethysmograpy, single breath nitrogen washout technique or gas dilution and selected controls. There is, however, a lack of data from general populations analyzing whether RSP is a valid proxy for true pulmonary restriction. We have validated RSP in relation to true pulmonary restriction in a general population where we have access to measurements of total lung capacity (TLC) and spirometry.

methodsThe data was from the Swedish CArdioPulmonary bioImage Study (SCAPIS Pilot), a general population-based study, comprising 983 adults aged 50-64. All subjects answered a respiratory questionnaire. Forced expiratory volume in 1 s (FEV

resultsThe prevalence of true pulmonary restriction was 5.4%, and the prevalence of RSP was 3.4%. The sensitivity of RSP to identify true pulmonary restriction was 0.34 (0.20-0.46), the corresponding specificity was 0.98 (0.97-0.99), and the positive likelihood ratio was 21.1 (11.3-39.4) and the negative likelihood ratio was 0.67 (0.55-0.81).

conclusionsRSP has low accuracy for identifying true pulmonary restriction. The results support previous observations that RSP is useful for ruling out true pulmonary restriction.

Indexed as

SpirometryTotal Lung CapacityFemaleHumansLung DiseasesMaleMiddle AgedReference valuesRestrictive lung diseaseRSPSCAPISTLCValidity

Identifiers

PMID32106839
PMCPMC7045734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.