Observational studyJournal of the American Heart Association2020
Does Incident Solar Ultraviolet Radiation Lower Blood Pressure?
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Systematic review on gene-sun exposure interactions in skin cancer.Molecular genetics & genomic medicine · 2023Pooled it
- Sunlight exposure in association with risk of lymphoid malignancy: a meta-analysis of observational studies.Cancer causes & control : CCC · 2021Pooled it
- Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022Trial
- Systemic effects of sunlight: 10-year review of cardiovascular, infection and cancer outcomes.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Review
- Blindspot: how sun exposure guidelines have ignored the health of individuals with skin of color.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Review
- Cutaneous microvascular function is reduced in winter compared with summer in healthy young adults.Physiological reports · 2026Article
- Dietary Supplementation withNutrients · 2026Article
- Association between meteorological factors and blood pressure variability in northern Guizhou, China.Frontiers in public health · 2026Article
- Impact of apparent temperature on specific cardiovascular disease admissions: a time-series study and association modification in Xiangyang, China.BMC public health · 2025Article
- Associations between season of conception and maternal and perinatal health: a prospective birth cohort study.Journal of global health · 2025Article
- Review
- Sunscreens: A narrative review.Skin health and disease · 2024Review
- Curcumin-Loaded Liposomes in Gel Protect the Skin of Mice against Oxidative Stress from Photodamage Induced by UV Irradiation.Gels (Basel, Switzerland) · 2024Article
- Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: evidence from the PoCOsteo study.Scientific reports · 2024Article
- Development and evaluation of machine learning models for predicting large-for-gestational-age newborns in women exposed to radiation prior to pregnancy.BMC medical informatics and decision making · 2024Article
- Photo-neuro-immuno-endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Assessing the relative importance of vitamin D deficiency in cardiovascular health.Frontiers in cardiovascular medicine · 2024Article
- Correlation between vitamin D levels and blood pressure in elderly hypertensive patients with osteoporosis.Frontiers in medicine · 2024Article
- The effect of daily UVA phototherapy for 2 weeks on clinic and 24-h blood pressure in individuals with mild hypertension.Journal of human hypertension · 2023Article
- Periodontal Disease and Other Adverse Health Outcomes Share Risk Factors, including Dietary Factors and Vitamin D Status.Nutrients · 2023Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Background Hypertension remains a leading global cause for premature death and disease. Most treatment guidelines emphasize the importance of risk factors, but not all are known, modifiable, or easily avoided. Population blood pressure correlates with latitude and is lower in summer than winter. Seasonal variations in sunlight exposure account for these differences, with temperature believed to be the main contributor. Recent research indicates that UV light enhances nitric oxide availability by mobilizing storage forms in the skin, suggesting incident solar UV radiation may lower blood pressure. We tested this hypothesis by exploring the association between environmental UV exposure and systolic blood pressure (SBP) in a large cohort of chronic hemodialysis patients in whom SBP is determined regularly. Methods and Results We studied 342 457 patients (36% black, 64% white) at 2178 US dialysis centers over 3 years. Incident UV radiation and temperature data for each clinic location were retrieved from the National Oceanic and Atmospheric Administration database. Linear mixed effects models with adjustment for ambient temperature, sex/age, body mass index, serum Na
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.