Evidence map›Paper›PMID 32106568›Full record

ArticleMolecules (Basel, Switzerland)2020

Trastuzumab Conjugated Superparamagnetic Iron Oxide Nanoparticles Labeled with

Edyta Cędrowska, Marek Pruszyński, Weronika Gawęda, Michał Żuk, Paweł Krysiński, Frank Bruchertseifer, Alfred Morgenstern, Maria-Argyro Karageorgou, Penelope Bouziotis, Aleksander Bilewicz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Development ofDrug delivery and translational research · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. New Radiopharmaceutical Tracers in Breast Cancer Diagnosis and Therapy.Anti-cancer agents in medicinal chemistry · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Molecules (Basel, Switzerland) · 2024
    Article
  11. Targeted Radium Alpha Therapy in the Era of Nanomedicine: In Vivo Results.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Review
  14. Metal-based nanoparticle in cancer treatment: lessons learned and challenges.Frontiers in bioengineering and biotechnology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Edyta CędrowskaInstitute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.
Marek PruszyńskiInstitute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0001-8835-2462
Weronika GawędaInstitute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.
Michał ŻukFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID 0000-0001-7121-9569
Paweł KrysińskiFaculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Frank BruchertseiferDepartment for Nuclear Safety and Security, Joint Research Centre, European Commission, 76125 Karlsruhe, Germany.
Alfred MorgensternDepartment for Nuclear Safety and Security, Joint Research Centre, European Commission, 76125 Karlsruhe, Germany.
Maria-Argyro KarageorgouInstitute of Nuclear & Radiological Sciences & Technology, Energy & Safety, N.C.S.R. 'Demokritos', Aghia Paraskevi, 15341 Athens, Greece.
Penelope BouziotisInstitute of Nuclear & Radiological Sciences & Technology, Energy & Safety, N.C.S.R. 'Demokritos', Aghia Paraskevi, 15341 Athens, Greece.ORCID 0000-0001-6778-2201
Aleksander BilewiczInstitute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.ORCID 0000-0003-2490-3303
Instytut Chemii i Techniki Jądrowej · PLJoint Research Centre · DEUniversity of Warsaw · PLNational and Kapodistrian University of Athens · GRNational Centre of Scientific Research "Demokritos" · GR

Funding

National Science Centre Poland UMO-2016/21/B/ST4/02133-OPUS.
6 · The paper itself

Abstract

It has been proven and confirmed in numerous repeated tests, that the use of a combination of several therapeutic methods gives much better treatment results than in the case of separate therapies. Particularly promising is the combination of ionizing radiation and magnetic hyperthermia in one drug. To achieve this objective, magnetite nanoparticles have been modified in their core with α emitter

Indexed as

RadioimmunotherapyActiniumAdo-Trastuzumab EmtansineAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsBreast NeoplasmsCell Line, TumorErb-b2 Receptor Tyrosine KinasesFemaleFerric CompoundsHumansHyperthermia, InducedMagneticsMagnetite NanoparticlesActiniumActinium-225Ado-Trastuzumab EmtansineAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFerric Compoundsferric oxideMagnetite Nanoparticleshyperthermiaradionuclide therapySPIONtrastuzumab

Identifiers

PMID32106568
PMCPMC7179151
OpenAlexW3007753153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.