Evidence map›Paper›PMID 32106544›Full record

ArticlePharmaceutics2020

Nanocrystals of Fusidic Acid for Dual Enhancement of Dermal Delivery and Antibacterial Activity: In Vitro, Ex Vivo and In Vivo Evaluation.

Iman S Ahmed, Osama S Elnahas, Nouran H Assar, Amany M Gad, Rania El Hosary

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Iman S AhmedDepartment of Pharmaceutics & Pharmaceutical Technology, College of Pharmacy, University of Sharjah, Sharjah 27272, UAE.
Osama S ElnahasDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt.
Nouran H AssarDepartment of Microbiology, National Organization for Drug Control and Research, Cairo 12553, Egypt.
Amany M GadDepartment of Pharmacology, National Organization for Drug Control and Research, Cairo 12553, Egypt.
Rania El HosaryDepartment of Pharmaceutics, National Organization for Drug Control and Research, Cairo 12553, Egypt.
National Organization for Drug Control and Research · EGOctober 6 University · EGUniversity of Sharjah · AE

Funding

University of Sharjah Research Project # 1801110228 To Iman Saad Ahmed
6 · The paper itself

Abstract

With the alarming rise in incidence of antibiotic-resistant bacteria and the scarcity of newly developed antibiotics, it is imperative that we design more effective formulations for already marketed antimicrobial agents. Fusidic acid (FA), one of the most widely used antibiotics in the topical treatment of several skin and eye infections, suffers from poor water-solubility, sub-optimal therapeutic efficacy, and a significant rise in FA-resistant

Indexed as

antibacterial activitydermal drug deliveryex-vivo studiesfusidic acidlyophilizationnanocrystalsrat excision wound infection model

Identifiers

PMID32106544
PMCPMC7150744
OpenAlexW3009032923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.