Evidence map›Paper›PMID 32106421›Full record

ArticleMedicina (Kaunas, Lithuania)2020

Predictors of Hyperuricemia after Kidney Transplantation: Association with Graft Function.

Inese Folkmane, Lilian Tzivian, Elizabete Folkmane, Elina Valdmane, Viktorija Kuzema, Aivars Petersons

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Inese FolkmaneFaculty of Medicine, Univeristy of Latvia, LV-1004 Riga, Latvia.
Lilian TzivianFaculty of Medicine, Univeristy of Latvia, LV-1004 Riga, Latvia.
Elizabete FolkmaneFaculty of Medicine, Univeristy of Latvia, LV-1004 Riga, Latvia.
Elina ValdmaneFaculty of Medicine, Univeristy of Latvia, LV-1004 Riga, Latvia.
Viktorija KuzemaPauls Stradins Clinical University Hospital, Centre of Nephrology of Latvia, LV-1002 Riga, Latvia.
Aivars PetersonsPauls Stradins Clinical University Hospital, Centre of Nephrology of Latvia, LV-1002 Riga, Latvia.ORCID 0000-0001-8109-1968
Pauls Stradiņš Clinical University Hospital · LVHolon Institute of Technology · ILRiga Stradiņš University · LVUniversity of Latvia · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn kidney transplant recipients (KTR), hyperuricemia (HU) is a commonly-observed phenomenon, due to calcineurin inhibitors and reduced kidney graft function. Factors predicting HU, and its association with graft function, remains equivocal.

methodsWe conducted a retrospective longitudinal study to assess factors associated with HU in KTR, and to determine risk factors associated with graft function, measured as glomerular filtration rate (GFR). Moreover, GFR > 60 mL/min/1.73 m

resultsThere were 144 patients (mean age 46.6 ± 13.9), with 42.4% of them having HU. Predictors of HU in KTR were the presence of cystic diseases (OR = 9.68 (3.13; 29.9)), the use of diuretics (OR = 4.23 (1.51; 11.9)), and the male gender (OR = 2.45 (1.07; 5.56)). Being a younger age, of female gender, with a normal BMI, and the absence of diuretic medications increased the possibility of normal GFR. HU was the effect modifier of the association between demographic, clinical, and biochemical factors and a normal GFR.

conclusionsFactors associated with HU in KTR: Presence of cystic diseases, diuretic use, and male gender. HU was the effect modifier of the association of demographic, clinical, and biochemical factors to GFR.

Indexed as

AdultCalcineurin InhibitorsDiureticsFemaleGlomerular Filtration RateGraft SurvivalHumansHyperuricemiaKidneyKidney Diseases, CysticKidney TransplantationLogistic ModelsLongitudinal StudiesMaleMiddle AgedPostoperative ComplicationsCalcineurin InhibitorsDiureticsUric AcidXanthine Oxidaseglomerular filtration ratehyperuricemiakidney transplantationuric acid

Identifiers

PMID32106421
PMCPMC7143203
OpenAlexW3007394530

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.