Evidence map›Paper›PMID 32106334›Full record

ArticleClinical cardiology2020

Four-year incidence of major adverse cardiovascular events in patients with atherosclerosis and atrial fibrillation.

Benjamin Miao, Adrian V Hernandez, Yuani M Roman, Mark J Alberts, Craig I Coleman, William L Baker

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  8. Review
  9. Concomitant diabetes with atrial fibrillation and anticoagulation management considerations.European heart journal supplements : journal of the European Society of Cardiology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Benjamin MiaoUniversity of Connecticut School of Pharmacy, Storrs, Connecticut, USA.ORCID https://orcid.org/0000-0002-2550-5027
Adrian V HernandezUniversity of Connecticut School of Pharmacy, Storrs, Connecticut, USA.
Yuani M RomanHartford Hospital, Hartford, Connecticut, USA.
Mark J AlbertsNeuroscience Institute, Hartford Hospital, Hartford, Connecticut, USA.
Craig I ColemanUniversity of Connecticut School of Pharmacy, Storrs, Connecticut, USA.
William L BakerUniversity of Connecticut School of Pharmacy, Storrs, Connecticut, USA.ORCID https://orcid.org/0000-0003-2172-0931
Hartford Hospital · US

Funding

BayerMedical Staff Internal Grant from Hartford Hospital
6 · The paper itself

Abstract

backgroundThere is a paucity of contemporary data assessing the implications of atrial fibrillation (AF) on major adverse cardiovascular events (MACE) in patients with or at high-risk for atherosclerotic disease managed in routine practice. HYPOTHESIS: We sought to evaluate the 4-year incidence of MACE in patients with or at risk of atherosclerotic disease in the presence of AF.

methodsUsing US MarketScan data, we identified AF patients ≥45 years old with billing codes indicating established coronary artery disease, cerebrovascular disease, or peripheral artery disease or the presence of ≥3 risk factors for atherosclerotic disease from January 1, 2013 to December 31, 2013 with a minimum of 4-years of available follow-up. We calculated the 4-year incidence of MACE (cardiovascular death or hospitalization with a primary billing code for myocardial infarction or ischemic stroke). Patients were further stratified by CHA

resultsWe identified 625,951 patients with 4-years of follow-up, of which 77,752 (12.4%) had comorbid AF. The median (25%, 75% range) CHA

conclusionComorbid AF carries a substantial risk of MACE in patients with or at risk of atherosclerotic disease. MACE risk increases with higher CHA

Indexed as

Health Status IndicatorsSeverity of Illness IndexAgedAtherosclerosisAtrial FibrillationFemaleHumansMiddle AgedPrognosisRisk AssessmentRisk Factorsatrial fibrillationestablished atherosclerotic diseasemajor adverse cardiovascular events

Identifiers

PMID32106334
PMCPMC7244295
OpenAlexW3008271510

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.