Evidence map›Paper›PMID 32105168›Full record

ArticleJournal of managed care & specialty pharmacy2020

Application of a Graphical Depiction of Longitudinal Study Designs to Managed Care Pharmacy Research.

Laura E Happe, Joshua D Brown, Justin Gatwood, Sebastian Schneeweiss, Shirley Wang

Abstract read
In one paragraph

Article in Journal of managed care & specialty pharmacy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Real-world evidence enhances decision making.Journal of managed care & specialty pharmacy · 2020
    Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura E HappeWingate University, Wingate, North Carolina; University of Florida, Gainesville; and Editor-in-chief, Journal of Managed Care & Specialty Pharmacy, Alexandria, Virginia.
Joshua D BrownUniversity of Florida, Gainesville, and Editorial Advisory Board member, Journal of Managed Care & Specialty Pharmacy, Alexandria, Virginia.
Justin GatwoodUniversity of Tennessee, Memphis, and Editorial Advisory Board member, Journal of Managed Care & Specialty Pharmacy, Alexandria, Virginia.
Sebastian SchneeweissDivision of Pharmacoepidemiology, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts.
Shirley WangDivision of Pharmacoepidemiology, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Managed care pharmacists apply real-world evidence (RWE) to support activities such as pipeline forecasting, clinical policy development, and contracting for pharmaceutical products. Managed care pharmacy researchers strive to produce studies that can be applied in practice. While asking the right research question is necessary, it is not sufficient. As with all studies, consumers of RWE look for internal and external validity, as well as sources of bias, to determine how the study findings can be applied in their work. To date, however, some of the safeguards that exist for clinical trials-such as public registration of study protocols-are lacking for RWE. Several leading professional organizations have initiatives dedicated to improving the credibility and reliability of such research. One component common to these initiatives is enhanced transparency and completeness of methodologic reporting. Graphical representations of study designs can improve the reporting and design of research conducted in health care databases, specifically by enhancing the transparency and clarity of often complex studies. As such, Schneeweiss et al. (2019) proposed a graphical framework for longitudinal study designs in health care databases. Herein, we apply this framework to 2 studies published in the

Indexed as

Research DesignDatabases, FactualHumansLongitudinal StudiesManaged Care ProgramsPharmaceutical ServicesPharmacistsPharmacy ResearchReproducibility of Results

Identifiers

PMID32105168
PMCPMC10391135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.