Evidence map›Paper›PMID 32105068›Full record

ArticleJournal of natural products2020

Using the Cancer Dependency Map to Identify the Mechanism of Action of a Cytotoxic Alkenyl Derivative from the Fruit of

Yun-Seo Kil, April L Risinger, Cora L Petersen, Huiyun Liang, Tanja Grkovic, Barry R O'Keefe, Susan L Mooberry, Robert H Cichewicz

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. LapsiHeliyon · 2025
    Review
  3. Article
  4. New Phenolic Lipids from the Leaves ofMolecules (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yun-Seo KilNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry & Biochemistry, Stephenson Life Science Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.
Cora L Petersen
Huiyun Liang
Tanja GrkovicNatural Products Support Group, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States.ORCID 0000-0002-6537-3997
Barry R O'KeefeNatural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, Maryland 21702, United States.ORCID 0000-0003-0772-4856
Susan L Mooberry
Robert H CichewiczNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry & Biochemistry, Stephenson Life Science Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.ORCID 0000-0003-0744-4117
The University of Texas Health Science Center at San Antonio · USUniversity of Oklahoma · USLeidos (United States) · USTarget (United States) · US

Funding

New Leads for Triple Negative Breast Cancer from Diverse Natural SourcesU01CA182740 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CICHEWICZ, ROBERT HENRY, MOOBERRY, SUSAN L · 2014 to 2018
$2.3M
Sourcing Bioactive Secondary Metabolites from Great Lakes FungiR01GM107490 · NIGMS · UNIVERSITY OF OKLAHOMA · PI CICHEWICZ, ROBERT HENRY, MOOBERRY, SUSAN L · 2014 to 2017
$2.3M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENCI NIH HHS U01 CA182740NIGMS NIH HHS R01 GM107490
6 · The paper itself

Abstract

An extract prepared from the fruit of

Indexed as

AnacardiaceaeAntineoplastic Agents, PhytogenicCell Line, TumorFruitHumansMolecular StructurePhytochemicalsPlant ExtractsVietnamAntineoplastic Agents, PhytogenicPhytochemicalsPlant Extracts

Identifiers

PMID32105068
PMCPMC7864215
OpenAlexW3008253092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.