Evidence map›Paper›PMID 32104816›Full record

ArticleLab on a chip2020

An acoustofluidic device for efficient mixing over a wide range of flow rates.

Hunter Bachman, Chuyi Chen, Joseph Rufo, Shuaiguo Zhao, Shujie Yang, Zhenhua Tian, Nitesh Nama, Po-Hsun Huang, Tony Jun Huang

Erratum issuedAbstract read
In one paragraph

Article in Lab on a chip, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  20. Emerging Technologies in Multi-Material Bioprinting.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hunter BachmanDepartment of Mechanical Engineering and Material Science, Duke University, Durham, NC 27708, USA. phhuang73@gmail.com tony.huang@duke.edu.
Chuyi Chen
Joseph Rufo
Shuaiguo Zhao
Shujie Yang
Zhenhua Tian
Nitesh Nama
Po-Hsun Huang
Tony Jun Huang

Funding

Extracellular vesicles and their ncRNA cargo as markers of trophoblast injuryR01HD086325 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2015 to 2019
$3.6M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platformR33CA223908 · NCI · NORTHEASTERN UNIVERSITY · PI EVENS, ANDREW M, HUANG, TONY JUN · 2018 to 2020
$1.2M
An integrated acoustofluidic droplet-sorting platform for classification of lymphocyte activity and functional phenotyping at single cell levelR01GM127714 · NIGMS · NORTHEASTERN UNIVERSITY · PI KONRY, TANIA TALI · 2018 to 2021
$1.2M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
National Science Foundation ECCS-1807601NCATS NIH HHS UG3 TR002978NCI NIH HHS R33 CA223908NICHD NIH HHS R01 HD086325NIGMS NIH HHS R01 GM127714NIGMS NIH HHS R01 GM132603US Army W81XWH-18-1-0242
6 · The paper itself

Abstract

Whether reagents and samples need to be combined to achieve a desired reaction, or precise concentrations of solutions need to be mixed and delivered downstream, thorough mixing remains a critical step in many microfluidics-based biological and chemical assays and analyses. To achieve complete mixing of fluids in microfluidic devices, researchers have utilized novel channel designs or active intervention to facilitate mass transport and exchange of fluids. However, many of these solutions have a major limitation: their design inherently limits their operational throughput; that is, different designs work at specific flow rates, whether that be low or high ranges, but have difficulties outside of their tailored design regimes. In this work, we present an acoustofluidic mixer that is capable of achieving efficient, thorough mixing across a broad range of flow rates (20-2000 μL min

Indexed as

Microfluidic Analytical TechniquesNanoparticlesLab-On-A-Chip DevicesMicrofluidicsPolymersPolymers

Identifiers

PMID32104816
PMCPMC7252412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.