Evidence map›Paper›PMID 32104739›Full record

ArticleCurrent medical mycology2019

In vitro activity of four triazole antifungal drugs against clinically common and uncommon yeast species.

Narges Aslani, Tahereh Shokohi, Mohammad Reza Ataollahi, Saham Ansari, Yousef Gholampour, Ali Khani Jeihooni, Mohammad Hosein Afsarian

Open access · diamondAbstract read
In one paragraph

Article in Current medical mycology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
  2. Antifungal Resistance of ClinicalIranian journal of public health · 2023
    Review
  3. Characterization ofCurrent medical mycology · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Narges AslaniInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Tahereh ShokohiDepartment of Medical Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Mohammad Reza AtaollahiDepartment of Medical Immunology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Saham AnsariDepartment of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Yousef GholampourDepartment of Internal Medicine, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Ali Khani JeihooniDepartment of Public Health, School of Health, Fasa University of Medical Sciences, Fasa, Iran.
Mohammad Hosein AfsarianDepartment of Medical Mycology and Parasitology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Fasa University of Medical Sciences · IRMazandaran University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRTabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIncidence of fungal infections caused by opportunistic fungal pathogens, such as yeasts and yeast-like species, has undergone an increase in otherwise healthy individuals. These pathogens account for high mortality and show reduced susceptibility to the routine antifungal drugs. Accordingly, antifungal susceptibility testing is an urgent need in the determination of the susceptibility spectrum of antifungals and selection of appropriate antifungal agents for the management of patients with fungal infection. MATERIALS AND

methodsThe present study was conducted on 110 yeast strains belonging to 15 species recovered from clinical specimens. Susceptibility of the isolates to four antifungal drugs (i.e., fluconazole, itraconazole, voriconazole, and posaconazole) was tested according to the Clinical and Laboratory Standards Institute guidelines M27-A3 and M27-S4.

resultsFluconazole exhibited no activity against 4.3% (n=2) of

conclusionThe current study provides insight into the antifungal susceptibility profiles of clinically common and uncommon yeast species to four triazole antifungal agents. According to our findings, voriconazole was the most active agent. Awareness about antifungal susceptibility patterns is highly helpful in the selection of appropriate antifungal drugs and identification of the efficiency of the currently used agents.

Indexed as

Antifungal agentsIn vitro susceptibilityYeast species

Identifiers

PMID32104739
PMCPMC7034789
OpenAlexW3004178817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.