Evidence map›Paper›PMID 32104602›Full record

ReviewCritical care research and practice2020

Vasopressors and Nutrition Therapy: Safe Dose for the Outset of Enteral Nutrition?

Luís Henrique Simo Es Covello, Marcella Giovana Gava-Brandolis, Melina Gouveia Castro, Martins Fidelis Dos Santos Netos, William Manzanares, Diogo Oliveira Toledo

Open access · goldAbstract readReview
In one paragraph

Review in Critical care research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Critical Care Dietitians' Practices in the Nutritional Management of Critically Ill Patients Receiving Vasopressors and Artificial Nutrition Support.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Luís Henrique Simo Es CovelloDepartment of Critical Care of Barretos Cancer Hospital, Barretos, Brazil.
Marcella Giovana Gava-BrandolisDepartment of Research of Hospital Sa˜o Luis Itaim, Sa˜o Paulo, Brazil.
Melina Gouveia CastroDepartment of Education of Hospital Israelita Albert Einstein, Sa˜o Paulo, Brazil.ORCID https://orcid.org/0000-0001-6023-6646
Martins Fidelis Dos Santos NetosDepartment of Science Information of Barretos Cancer Hospital, Barretos, Brazil.
William ManzanaresDepartment of Critical Care, University Hospital of Universidad de la Republica (UDELAR), Montevideo, Uruguay.
Diogo Oliveira ToledoDepartment of Critical Care of Hospital Israelita Albert Einstein, Sa˜o Paulo, Brazil.
Hospital de Câncer de Barretos · BRHospital Israelita Albert Einstein · BRHospital São Paulo · BRUniversidad de la República de Uruguay · UY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPatients with hemodynamic instability need to receive intensive treatment as fluid replacement and vasoactive drugs. In the meantime, it is supposed to initiate nutritional therapy within 24 to 48 hours after admission to the intensive care unit (ICU), as an essential part of patient's intensive care and better outcomes. However, there are many controversies tangential to the prescription of enteral nutrition (EN) concomitant to the use of vasopressor and its doses. In this way, the present study aimed to identify what the literature presents of evidence to guide the clinical practice concerning the safe dose of vasopressors for the initiation of nutritional therapy in critically ill patients.

methodsThis review was carried out in PubMed, ProQuest, Web of Science, and Medline databases. The descriptors were used to perform the search strategy: Critical Care, Intensive Care Units, Vasoconstrictor Agents, and Enteral Nutrition. Inclusion criteria were patients of both genders, over 18 years of age, using vasoactive drugs, with the possibility of receiving EN therapy, and articles written in English, Portuguese, and Spanish. In addition, exclusion criteria were case reports, non-papers, and repeated papers.

results10 articles met our inclusion criteria.

conclusionIt was observed that there are many controversies about the supply of EN in critically ill patients using vasopressor, especially about the safe dose, and it was not possible to identify a cutoff value for the beginning therapy. Despite the drug doses, clinical signs are still the most important parameters in the evaluation of EN tolerance.

Identifiers

PMID32104602
PMCPMC7035530
OpenAlexW3005763882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.