Evidence map›Paper›PMID 32104544›Full record

ArticleOxidative medicine and cellular longevity2020

Fucoidan Ameliorates Oxidative Stress, Inflammation, DNA Damage, and Hepatorenal Injuries in Diabetic Rats Intoxicated with Aflatoxin B

Mohammed S Aleissa, Saad Alkahtani, Mabrouk Attia Abd Eldaim, Ali Meawad Ahmed, Simona G Bungău, Bader Almutairi, May Bin-Jumah, Abdullah A AlKahtane, Mohamed S Alyousif, Mohamed M Abdel-Daim

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Review
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  12. Article
  13. Maintenance of homeostasis by TLR4 ligands.Frontiers in immunology · 2024
    Review
  14. Article
  15. Article
  16. Fucoidan fromBiomedicines · 2023
    Article
  17. Article
  18. Promising role ofHeliyon · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Mohammed S AleissaDepartment of Biology, Science College, Al Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Saad AlkahtaniDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Mabrouk Attia Abd EldaimDepartment of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, Menoufia University, 32511, Egypt.ORCID https://orcid.org/0000-0001-9842-9777
Ali Meawad AhmedDepartment of Food Hygiene, Faculty of Veterinary Medicine, Suez Canal University, 41522 Ismailia, Egypt.
Simona G BungăuDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.ORCID https://orcid.org/0000-0003-3236-1292
Bader AlmutairiDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
May Bin-JumahBiology Department, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-3017-9924
Abdullah A AlKahtaneDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Mohamed S AlyousifDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0001-7673-7437
Mohamed M Abdel-DaimDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID https://orcid.org/0000-0002-4341-2713
King Saud University · SASuez Canal University · EGImam Mohammad ibn Saud Islamic University · SAMenoufia University · EGPrincess Nourah bint Abdulrahman University · SAUniversity of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study was carried out to evaluate the ameliorative effect of fucoidan against aflatoxicosis-induced hepatorenal toxicity in streptozotocin-induced diabetic rats. Sixty-four Wister albino male rats were randomly assigned into eight groups (8 rats each) that received normal saline, fucoidan (FUC) at 100 mg/kg/day orally for 4 weeks, streptozotocin (STZ) at 50 mg/kg/i.p. single dose, STZ plus FUC, aflatoxin B

Indexed as

Aflatoxin B1AnimalsAntioxidantsCatalaseDNA DamageGlutathioneInflammationLipid PeroxidationLiverMaleOxidative StressPolysaccharidesRatsRats, WistarStreptozocinSuperoxide DismutaseAflatoxin B1AntioxidantsCatalasefucoidanGlutathionePolysaccharidesStreptozocinSuperoxide Dismutase

Identifiers

PMID32104544
PMCPMC7035576
OpenAlexW3004458192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.