Evidence map›Paper›PMID 32104537›Full record

ArticleOxidative medicine and cellular longevity2020

Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.

Peipei Wang, Mingyi Zhao, Zhiheng Chen, Guojiao Wu, Masayuki Fujino, Chen Zhang, Wenjuan Zhou, Mengwen Zhao, Shin-Ichi Hirano, Xiao-Kang Li and 1 more

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Review
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  6. Review
  7. The Protective Role of Molecular Hydrogen in Ischemia/Reperfusion Injury.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.Oxidative medicine and cellular longevity · 2022
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Peipei WangDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-1431-2139
Mingyi ZhaoDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-2884-0736
Zhiheng ChenDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.
Guojiao WuDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.
Masayuki FujinoDivision of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan.
Chen ZhangDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.
Wenjuan ZhouDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.
Mengwen ZhaoDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.
Shin-Ichi HiranoMiZ Co., Ltd., Kanagawa, Japan.
Xiao-Kang LiDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-0897-2141
Lingling ZhaoDepartment of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-0835-4378
Central South University · CNNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal hypoxic-ischemic encephalopathy (HIE) is a leading cause of death in neonates with no effective treatments. Recent advancements in hydrogen (H

Indexed as

MAP Kinase Signaling SystemAnimalsAnimals, NewbornAntioxidantsApoptosisbcl-2-Associated X ProteinCaspase 3FemaleHeme Oxygenase-1HydrogenHypoxia-Ischemia, BrainJNK Mitogen-Activated Protein KinasesLearningMaleMemoryMitogen-Activated Protein Kinase KinasesAntioxidantsbcl-2-Associated X ProteinCasp3 protein, ratCaspase 3Heme Oxygenase-1HydrogenJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein Kinase KinasesNeuroprotective Agentsp38 Mitogen-Activated Protein KinasesPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, ratSirtuin 1

Identifiers

PMID32104537
PMCPMC7040418
OpenAlexW3005592155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.