Evidence map›Paper›PMID 32104533›Full record

ArticleOxidative medicine and cellular longevity2020

The HIPPO Transducer YAP and Its Targets CTGF and Cyr61 Drive a Paracrine Signalling in Cold Atmospheric Plasma-Mediated Wound Healing.

Debarati Shome, Thomas von Woedtke, Katharina Riedel, Kai Masur

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Cold Atmospheric Plasma in Wound Healing: Molecular Mechanism of Action.International journal of molecular sciences · 2026
    Review
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  16. Wound healing and signaling pathways.Open life sciences · 2025
    Review
  17. [Mechanism of cold atmospheric plasma in treatment of chronic skin ulcer].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Review
  18. Cysteine-rich 61 inhibition attenuates hepatic insulin resistance and improves lipid metabolism in high-fat diet fed mice and HepG2 cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Debarati ShomeLeibniz Institute for Plasma Science and Technology, A Member of the Leibniz Research Alliance Leibniz Health Technology, Felix-Hausdorff-Straße 2, Greifswald 17489, Germany.ORCID https://orcid.org/0000-0001-5992-883X
Thomas von WoedtkeLeibniz Institute for Plasma Science and Technology, A Member of the Leibniz Research Alliance Leibniz Health Technology, Felix-Hausdorff-Straße 2, Greifswald 17489, Germany.
Katharina RiedelInstitute for Microbiology, University of Greifswald, Felix-Hausdorff-Straße 8, Greifswald 17489, Germany.
Kai MasurLeibniz Institute for Plasma Science and Technology, A Member of the Leibniz Research Alliance Leibniz Health Technology, Felix-Hausdorff-Straße 2, Greifswald 17489, Germany.ORCID https://orcid.org/0000-0001-7115-2122
Leibniz Institute for Plasma Science and Technology · DEUniversität Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive species play a pivotal role in orchestrating wound healing responses. They act as secondary messengers and drive redox-signalling pathways that are involved in the homeostatic, inflammatory, proliferative, and remodelling phases of wound healing. The application of Cold Atmospheric Plasma (CAP) to the wound site produces a profusion of short- and long-lived reactive species that have been demonstrated to be effective in promoting wound healing; however, knowledge of the mechanisms underlying CAP-mediated wound healing remains scarce. To address this, an

Indexed as

Paracrine CommunicationAcetylcysteineAdaptor Proteins, Signal TransducingCell MovementCells, CulturedCoculture TechniquesConnective Tissue Growth FactorCysteine-Rich Protein 61FibroblastsGene Expression RegulationHumansKeratinocytesPlasma GasesReactive Oxygen SpeciesRecombinant ProteinsTranscription FactorsAcetylcysteineAdaptor Proteins, Signal TransducingCCN1 protein, humanCCN2 protein, humanConnective Tissue Growth FactorCysteine-Rich Protein 61Plasma GasesReactive Oxygen SpeciesRecombinant ProteinsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteins

Identifiers

PMID32104533
PMCPMC7040405
OpenAlexW3005652542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.