Evidence map›Paper›PMID 32104501›Full record

ArticleTheranostics2020

Glutathione-responsive disassembly of disulfide dicyanine for tumor imaging with reduction in background signal intensity.

Shanyan Mo, Xiaoting Zhang, Sadaf Hameed, Yiming Zhou, Zhifei Dai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Self-accelerating HTheranostics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shanyan MoDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Xiaoting ZhangDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Sadaf HameedDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Yiming ZhouDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Zhifei DaiDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
Peking University · CNBeijing University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-infrared (NIR) fluorescence imaging has been proved as an effective modality in identifying the tumor border and distinguishing the tumor cells from healthy tissue during the oncological surgery. Developing NIR fluorescent probes with high tumor to background (T/B) signal is essential for the complete debulking of the tumor, which will prolong the survival rate of tumor patients. However, the nonspecific binding and "always-on" properties of the conventional fluorescent probes leads to high background signals and poor specificity.

Indexed as

AnimalsColoring AgentsDiagnostic ImagingDisulfidesFemaleFluorescent DyesGlutathioneHumansMiceMice, Inbred BALB CMolecular Probe TechniquesNeoplasmsOptical ImagingTumor MicroenvironmentColoring AgentsDisulfidesFluorescent DyesGlutathionedisulfide dicyanineFluorescence imagingfluorescence quenchingmolecular probetumor response

Identifiers

PMID32104501
PMCPMC7019170
OpenAlexW3003366398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.