Evidence map›Paper›PMID 32104463›Full record

ArticleAsian journal of pharmaceutical sciences2019

Study of penetration mechanism of labrasol on rabbit cornea by Ussing chamber, RT-PCR assay, Western blot and immunohistochemistry.

Pan Guo, Nan Li, Lili Fan, Jun Lu, Boying Liu, Bing Zhang, Yumei Wu, Zhidong Liu, Jiawei Li, Jiaxin Pi and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Lipid-based nanoparticles: innovations in ocular drug delivery.Frontiers in molecular biosciences · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Pan GuoTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Nan LiTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Lili FanTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Jun LuSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300193, China.
Boying LiuTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Bing ZhangTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Yumei WuTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Zhidong LiuTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Jiawei LiEngineering Research Center of Modern Chinese Medicine Discovery and Preparation, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Jiaxin PiTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Dongli QiTianjin State Key Laboratory of Modern Chinese Medicine, The Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No. 88 Yuquan Road, Tianjin 300193, China.
Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Labrasol, as a non-ionic surfactant, can enhance the permeation and absorption of drugs, and is extensively used in topical, transdermal, and oral pharmaceutical preparations as an emulsifier and absorption enhancer. Recent studies in our laboratory have indicated that labrasol has a strong absorption enhancing effect on different types of drugs

Indexed as

Enhanced corneal permeationImmunohistochemistryLabrasolTight junctions associated proteinsUssing chamberWestern blot

Identifiers

PMID32104463
PMCPMC7032126
OpenAlexW2808193082

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.