Evidence map›Paper›PMID 32104331›Full record

ArticleAsian journal of pharmaceutical sciences2017

Influence of pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury model rats by HPLC-MS.

Huiyan Shi, Chenzhi Hou, Liqiang Gu, Zhe Wei, Hang Xing, Meiyu Zhang, Shixiao Wang, Longshan Zhao, Kaishun Bi, Xiaohui Chen

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Evaluation of solid-lipid nanoparticles formulation of methotrexate for anti-psoriatic activity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huiyan ShiSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Chenzhi HouSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Liqiang GuSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhe WeiSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Hang XingSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Meiyu ZhangSchool of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shixiao WangSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Longshan ZhaoSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Kaishun BiSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiaohui ChenSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats. A simple and efficient high performance liquid chromatography coupled with mass spectrometry (HPLC-MS) method was developed to determine methotrexate in rat plasma. Methotrexate and syringic acid (internal standard) were extracted from rat plasma samples by protein precipitation with acetonitrile. The analysis was performed on a CAPCELL PAK C

Indexed as

HPLC-MSMethotrexatePharmacokinetic parametersPiperazine ferulate

Identifiers

PMID32104331
PMCPMC7032110
OpenAlexW2521986535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.