Evidence map›Paper›PMID 32104264›Full record

ArticleExperimental and therapeutic medicine2020

Low expression and hypermethylation of FOXP3 in regulatory T cells are associated with asthma in children.

Xiaohua Zhu, Qiang Chen, Zhiqiang Liu, Daya Luo, Lan Li, Ying Zhong

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. T Regulatory Mechanisms in Airway and Interstitial Lung Disease.Seminars in respiratory and critical care medicine · 2025
    Review
  5. Engineering nanoparticle therapeutics for food allergy.The Journal of allergy and clinical immunology · 2024
    Review
  6. Article
  7. Article
  8. Epigenetic regulation of immune function in asthma.The Journal of allergy and clinical immunology · 2022
    Review
  9. Article
  10. Prospects for Use of Single-Cell Sequencing to Assess DNA Methylation in Asthma.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaohua ZhuRespiratory Department, Jiangxi Provincial Children's Hospital, Nanchang, Jiangxi 330006, P.R. China.
Qiang ChenRespiratory Department, Jiangxi Provincial Children's Hospital, Nanchang, Jiangxi 330006, P.R. China.
Zhiqiang LiuClinical Laboratory, Jiangxi Children's Hospital, Nanchang, Jiangxi 330006, P.R. China.
Daya LuoDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Lan LiRespiratory Department, Jiangxi Provincial Children's Hospital, Nanchang, Jiangxi 330006, P.R. China.
Ying ZhongGraduate School of Medicine, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Jiangxi Provincial Children's Hospital · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to determine the expression and methylation levels of forkhead transcription factor P3 (FOXP3) in peripheral blood CD4

Indexed as

asthmachildrenforkhead transcription factor P3methylationregulatory T cells

Identifiers

PMID32104264
PMCPMC7027311
OpenAlexW2999574765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.