Evidence map›Paper›PMID 32104209›Full record

ArticleEcancermedicalscience2020

Health-related quality of life before and during chemotherapy in patients with early-stage breast cancer.

Monique Binotto, Tomás Reinert, Gustavo Werutsky, Facundo Zaffaroni, Gilberto Schwartsmann

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecancermedicalscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05072197 (The Effectiveness of a Mobile Application as a Support Tool for the Treatment of Women With Breast Cancer Undergoing Chemotherapy), which is not on this map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05072197 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Effectiveness of a Mobile Application as a Support Tool for the Treatment of Women With Breast Cancer Undergoing Chemotherapy: A Randomized Controlled Trial

TypeinterventionalSponsorCheng-Hsin General HospitalRan2021 to 2023Enrolled70ConditionsBreast NeoplasmsArmsMobile device as a support tool for the treatment of women with breast cancer undergoing chemotherapy
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  6. Chan-Chuang qigong with breathing meditation improves quality of life and interoceptive awareness in patients with breast cancer: a randomised controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  20. Chemotherapy: how to reduce its adverse effects while maintaining the potency?Medical oncology (Northwood, London, England) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Monique BinottoPostgraduate Program in Clinical Research, Hospital de Clínicas de Porto Alegre, HCPA, Porto Alegre, RS 90035-007, Brazil.
Tomás ReinertCentro de Pesquisa da Serra Gaúcha, CEPESG, Caxias do Sul, RS 95020-450, Brazil.
Gustavo WerutskyLatin American Cooperative Oncology Group, LACOG, Porto Alegre, RS 90619-900, Brazil.
Facundo ZaffaroniLatin American Cooperative Oncology Group, LACOG, Porto Alegre, RS 90619-900, Brazil.
Gilberto SchwartsmannPostgraduate Program in Clinical Research, Hospital de Clínicas de Porto Alegre, HCPA, Porto Alegre, RS 90035-007, Brazil.
Twitter (United States) · USEastern Cooperative Oncology Group · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIdentify the main changes in the health-related quality of life (HRQoL) of women diagnosed with breast cancer (BC) undergoing chemotherapy.

methodsProspective cohort study that included 33 women diagnosed with clinical stages I-III BC and who underwent adjuvant chemotherapy. HRQoL was assessed using the EORTC QLQ-C30 and EORTC QLQ-BR23 instruments 1 week before the start of chemotherapy and during the third month of chemotherapy.

resultsThere was a decline in the HRQoL scores of patients during treatment. Therefore, chemotherapy alters the patient's perceptions of their HRQoL since there is a decrease in global health status/quality of life (QoL) and functional scales such as physical functioning, role functioning, emotional functioning, social functioning, body image, sexual function and sexual enjoyment. We also observed an increase in side effects related to the systemic therapy, fatigue, nausea and vomiting, insomnia, appetite loss and diarrhoea, despite a decrease in breast symptoms and arm symptoms.

conclusionsHRQoL was negatively affected during chemotherapy. Even though HRQoL assessment is a useful method for optimising patients' care, its implementation into clinical practice remains a challenge. Since side effects are very often underestimated, we consider that the evaluation of HRQoL parameters should be done for BC patients treated with chemotherapy.

Indexed as

breast cancercancerhealth-related quality of lifepatient-reported outcomes

Identifiers

PMID32104209
PMCPMC7039692
OpenAlexW3001935830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.