Evidence map›Paper›PMID 32104128›Full record

ArticleJournal of blood medicine2020

Phenotype Frequencies of Major Blood Group Systems (Rh, Kell, Kidd, Duffy, MNS, P, Lewis, and Lutheran) Among Blood Donors in the Eastern Region of Saudi Arabia.

Amani Y Owaidah, Noor M Naffaa, Arwa Alumran, Faisal Alzahrani

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 47 citations in OpenAlex.

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  13. Tropical medicine and infectious disease · 2023
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  14. When the available blood supply mismatches the needs of the patient.Blood transfusion = Trasfusione del sangue · 2023
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  16. Identification of Lutheran Blood Groups and Genetic Variants withinTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  17. High-Throughput Next-Generation Sequencing of the Kidd Blood Group: Unexpected Antigen Expression Properties of Four Alleles and Detection of Novel Variants.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amani Y OwaidahDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-5224-175X
Noor M NaffaaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-3561-2379
Arwa AlumranDepartment of Health Information Management and Technology, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0001-6454-3678
Faisal AlzahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0003-4425-6502
Imam Abdulrahman Bin Faisal University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe understanding of blood group phenotypes in Saudi Arabia is limited to the ABO and Rh blood groups. Data for the other major blood group phenotypes in different populations have been widely studied and used as a reference for identifying antigen-negative blood in hospital blood banks. Such information is crucial for facilitating the challenging task of providing antigen-negative blood for patients with multiple antibodies.

objectiveThe aim of this study was to determine the frequency of the major blood group phenotypes in the Eastern region of Saudi Arabia and compare them to phenotypes in other populations.

methodsA total of 100 volunteer Saudi donors were included in this study. Red blood cells from the donors were subjected to antigen typing of the major blood group systems (Rh, Kell, Kidd, Duffy, MNS, Lewis, Lutheran, and P) using the gel microtube technique.

resultsFrom the Rh blood group system, the e antigen was found in 97% of donors, followed by c at 86%. The Cellano (k) antigen of the Kell system was found in all donors, whereas the Kell (K) antigen was only found in 8 % of donors. The K+k- phenotype was not detected in our study. Unexpectedly, for the Duffy blood group system, the null phenotype Fy(a-b-) was found in 61% of donors. In the MNS blood group system, M+N-S+s+ was the most common phenotype at 24%.

conclusionThe frequency of blood group phenotypes in the Eastern region of Saudi Arabia differs from that in other populations because of the diverse ethnic backgrounds of those living in that region. The findings of this study can be used to establish a local donor registry to help provide antigen-negative blood for patients with unexpected antibodies or to create an in-house antibody identification panel to add to the commercial panel that would be useful for confirming antibody identification results.

Indexed as

alloimmunizationblood groupsphenotype frequenciesSaudi Arabia

Identifiers

PMID32104128
PMCPMC7025674
OpenAlexW3006255422

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.