Evidence map›Paper›PMID 32104007›Full record

ArticleInfection and drug resistance2020

Synergistic and Antagonistic Effects of Metal Nanoparticles in Combination with Antibiotics Against Some Reference Strains of Pathogenic Microorganisms.

Usama H Abo-Shama, Hanem El-Gendy, Walid S Mousa, Ragaa A Hamouda, Wesam E Yousuf, Helal F Hetta, Eman E Abdeen

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 157 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. HypervirulentPharmaceuticals (Basel, Switzerland) · 2025
    Review
  19. Review
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Usama H Abo-ShamaDepartment of Microbiology and Immunology, Faculty of Veterinary Medicine, Sohag University, Sohag 82524, Egypt.ORCID 0000-0002-9456-3837
Hanem El-GendyDepartment of Pharmacology, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt.
Walid S MousaDepartment of Animal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt.
Ragaa A HamoudaGenetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.
Wesam E YousufGenetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.
Helal F HettaDepartment of Medical Microbiology & Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0001-8541-7304
Eman E AbdeenDepartment of Bacteriology, Mycology and Immunology, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt.
University of Sadat City · EGAssiut University · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimNanosized inorganic antibacterial materials have received increasing attention in recent years. The present study aimed to determine the antimicrobial activity of silver (Ag) and zinc oxide (ZnO) nanoparticles alone and in combination with antibiotics against reference strains of pathogenic microorganisms as

methodsThe antimicrobial effect of metal-nanoparticles (AgNPs and ZnONPS) and in combination with antibiotics was studied using the normal disc-diffusion method.

resultsBoth AgNPs and ZnONPs had increased antibacterial activity with an increase in their concentration against Gram-positive bacterium (

conclusionAgNPs and ZnONPs demonstrate a good synergistic effect with antibiotics and this may open the door for a future combination therapy against pathogenic bacteria.

Indexed as

AgNPsantimicrobial activity E. coli Staph. aureusCandida albicansSalmonella sppZnONPs

Identifiers

PMID32104007
PMCPMC7012269
OpenAlexW3004841967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.