Evidence map›Paper›PMID 32103950›Full record

ArticleInternational journal of nanomedicine2020

Synthesis of Silver Nanoparticle Employing Corn Cob Xylan as a Reducing Agent with Anti-

Talita Katiane Brito, Rony Lucas Silva Viana, Cláudia Jassica Gonçalves Moreno, Jefferson da Silva Barbosa, Francimar Lopes de Sousa Júnior, Mayara Jane Campos de Medeiros, Raniere Fagundes Melo-Silveira, Jailma Almeida-Lima, Daniel de Lima Pontes, Marcelo Sousa Silva and 1 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Use of nanoparticles, a modern means of drug delivery, against cryptosporidiosis.Journal of advanced veterinary and animal research · 2023
    Review
  4. Review
  5. Review
  6. Review
  7. Apoptotic changes in the intestinal epithelium ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Talita Katiane Brito *Postgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59012-570, Brazil.ORCID 0000-0002-3113-7187
Rony Lucas Silva Viana *Laboratory of Biotechnology of Natural Polymers (BIOPOL), Department of Biochemistry, Center of Biosciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.ORCID 0000-0001-5015-9595
Cláudia Jassica Gonçalves MorenoPostgraduate Program in Biochemistry, Federal University of Rio Grande do Norte UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.ORCID 0000-0002-6948-9823
Jefferson da Silva BarbosaPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59012-570, Brazil.ORCID 0000-0003-1237-5785
Francimar Lopes de Sousa JúniorLaboratory of Chemistry of Coordination and Polymers (LQCPol), Institute of Chemistry, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.ORCID 0000-0001-9300-8623
Mayara Jane Campos de MedeirosLaboratory of Chemistry of Coordination and Polymers (LQCPol), Institute of Chemistry, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.
Raniere Fagundes Melo-SilveiraLaboratory of Biotechnology of Natural Polymers (BIOPOL), Department of Biochemistry, Center of Biosciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.
Jailma Almeida-LimaPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59012-570, Brazil.
Daniel de Lima PontesLaboratory of Chemistry of Coordination and Polymers (LQCPol), Institute of Chemistry, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.
Marcelo Sousa SilvaPostgraduate Program in Biochemistry, Federal University of Rio Grande do Norte UFRN), Natal, Rio Grande do Norte 59078-970, Brazil.ORCID 0000-0002-1000-0149
Hugo Alexandre Oliveira RochaPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte 59012-570, Brazil.ORCID 0000-0003-2252-1221

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChagas disease, also known as American Trypanosomiasis, is caused by the protozoan

methodsUltraviolet-visible spectroscopy, Fourier transform infrared spectroscopy (FITR), Raman spectroscopy, energy-dispersive X-ray spectroscopy (EDS), scanning electron microscopy, atomic force microscopy, plasma optical emission spectroscopy (ICP-OES), dynamic light scattering (DLS) have been used to characterize the silver-xylan nanoparticles (NX). Their cytotoxicity was evaluated with 3-bromo(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) test. MTT and flow cytometry were used to ascertain the anti-

resultsUV-Vis spectroscopy gave plasmon resonance ranging between 400 and 450 nm while FITC and Raman spectroscopy proved nano interface functionalized with xylan. ICP-OES data showed NX with xylan (81%) and silver (19%). EDS showed NX consisting of carbon (59.4%), oxygen (26.2%) and silver (4.8%) main elements. Spherical NX of 55 nm average size has been depicted with SEM and AFM, while DLS showed 102 ± 1.7 nm NX. The NX displayed negligible cytotoxicity (2000 µg/mL). NX (100 µg/mL) was more effective, regardless of experiment time, in affecting the ability of parasites to reduce MTT than BZN (100 µg/mL). In addition, NX (100 µg/mL) induced death of 95% of parasites by necrosis.

conclusionThis is the first time silver nanoparticles are presented as an anti-

Indexed as

AnimalsChagas DiseaseDynamic Light ScatteringMetal NanoparticlesMiceMicroscopy, Atomic ForceRAW 264.7 CellsSilverSpectrometry, X-Ray EmissionSpectrophotometry, UltravioletSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanTrypanocidal AgentsTrypanosoma cruziXylansZea maysSilverTrypanocidal AgentsXylansbenznidazolesilver nanoparticlesTrypanosoma cruzixylan

Identifiers

PMID32103950
PMCPMC7026134

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.