Evidence map›Paper›PMID 32103937›Full record

ArticleInternational journal of nanomedicine2020

Ultrasonic Nanoemulsification of

M Joyce Nirmala, Latha Durai, Kagitala Anvesh Rao, R Nagarajan

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Nanoemulsion-enhanced cytotoxicity ofFrontiers in oncology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Effects ofFood science & nutrition · 2023
    Article
  10. Review
  11. Nanoemulsion and Nanogel ContainingJournal of tropical medicine · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Evaluation of the Effects ofMedicina (Kaunas, Lithuania) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

M Joyce NirmalaDepartment of Chemical Engineering, Indian Institute of Technology Madras, Chennai 600 036, India.ORCID 0000-0002-2527-4708
Latha DuraiDepartment of Biotechnology, Bhupat & Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India.
Kagitala Anvesh RaoDepartment of Chemical Engineering, Indian Institute of Technology Madras, Chennai 600 036, India.ORCID 0000-0001-6048-9205
R NagarajanDepartment of Chemical Engineering, Indian Institute of Technology Madras, Chennai 600 036, India.ORCID 0000-0003-1430-6644
Indian Institute of Technology Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and studyCumin seed oil (extracted from

methodsThe cumin nanoemulsion was prepared with Tween 80 non-ionic surfactant employing ultra-sonication technology. The anticancer activity of the nanoscale-based emulsion was evaluated through cell viability (MTT), antiproliferation evaluation through clonogenic assay, and apoptosis through Annexin V-FITC assay. Agar well diffusion was used to study the antimicrobial activity, and this was supported by membrane integrity analysis.

resultsA thorough study of process parameters, aimed at obtaining the optimal surface concentration and emulsification time, was completed. GC-MS data indicated cumaldehyde as a major component. The resultant droplet diameter after a sonication time of 5 min was 10.4 ± 0.5 nm. MTT assay revealed the IC

conclusionThis study provides definitive evidence for cumin essential oil nanoemulsion as a legitimate plant-based medicine that can bypass the drawbacks of the present aggressive treatment of cancer, can overcome the antimicrobial resistance, and can also meet all prerequisites.

Indexed as

Anti-Bacterial AgentsAntineoplastic Agents, PhytogenicApoptosisCell Line, TumorCell ProliferationCell SurvivalCuminumEmulsionsGas Chromatography-Mass SpectrometryHumansNanostructuresOils, VolatileSeedsStaphylococcus aureusUltrasonicsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicEmulsionsOils, Volatileantibacterial activityanticancer activityapoptosiscumin oilnanoemulsiontongue carcinoma cell line

Identifiers

PMID32103937
PMCPMC7008196
OpenAlexW3004807574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.