Evidence map›Paper›PMID 32103646›Full record

ArticleJournal of Korean medical science2020

Hyperuricemia Is Not Predictive of Long-Term Outcome in Patients with Stable Chronic Obstructive Pulmonary Disease.

Jae Joon Hwang, Yeon Mok Oh, Chin Kook Rhee, Kwang Ha Yoo, Yong Bum Park, Ho Il Yoon, Seong Yong Lim, Ji Hyun Lee, Eun Kyung Kim, Tae Hyung Kim and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Jae Joon HwangDepartment of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gang-Dong, School of Medicine, Kyung Hee University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1832-1024
Yeon Mok OhDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0116-4683
Chin Kook RheeDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-4533-7937
Kwang Ha YooDepartment of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9969-2657
Yong Bum ParkDivision of Pulmonology, Department of Internal Medicine, Hallym University Gangdong Sacred Heart Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8810-6077
Ho Il YoonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-2896-4576
Seong Yong LimDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8098-3622
Ji Hyun LeeDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0002-8287-5470
Eun Kyung KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Bundang CHA Medical Center, CHA University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0001-6239-1682
Tae Hyung KimDivision of Pulmonology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.ORCID https://orcid.org/0000-0002-3863-7854
Sei Won LeeDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4814-6730
Sang Do LeeDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8189-4509
Jae Seung LeeDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. jsdoc1186@hanmail.net.ORCID https://orcid.org/0000-0003-4130-1486
KOLD Group
Ulsan College · KRCHA University Bundang Medical Center · KRHallym University · KRHanyang University Guri Hospital · KRKangbuk Samsung Hospital · KRKonkuk University Medical Center · KRKyung Hee University Hospital at Gangdong · KRSeoul National University Bundang Hospital · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KR

Funding

Ministry of Health and Welfare A102065Ministry of Health and Welfare HI10C2020
6 · The paper itself

Abstract

backgroundAlthough the association of hyperuricemia with an increased risk of mortality has been demonstrated in the context of acute exacerbation of chronic obstructive pulmonary disease (COPD), the long-term outcomes of hyperuricemia have not been studied in the case of stable COPD.

methodsWe retrospectively analyzed baseline data of 240 men with stable COPD enrolled in the Korea Obstructive Lung Disease cohort. We evaluated associations between serum uric acid levels and clinical parameters, risk factors for all-cause mortality, and acute exacerbation of COPD.

resultsThe mean age of subjects was 66.4 ± 7.7 years, and the median follow-up time was 5.9 years. We identified no significant difference in terms of lung function or laboratory findings between patients with hyperuricemia and those without. Serum uric acid level was negatively associated with systemic inflammation indicated by neutrophil-lymphocyte ratio (

conclusionAmong men with stable COPD, hyperuricemia is not an independent predictor of all-cause mortality or future acute exacerbation of COPD. These results differ from those of previous studies on patients with acute exacerbation of COPD.

Indexed as

AgedFemaleHumansHyperuricemiaKaplan-Meier EstimateLungLymphocytesMaleMiddle AgedNeutrophilsProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveRetrospective StudiesRisk FactorsUric AcidUric AcidAcute ExacerbationChronic Obstructive Pulmonary DiseaseHyperuricemiaInflammationMortality

Identifiers

PMID32103646
PMCPMC7049621
OpenAlexW3005056259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.